Department of Urology, Daping Hospital, Army Medical University, Chongqing, China.
Department of Urology, Chongqing Renji Hospital, University of Chinese Academy of Sciences, Chongqing, China.
Int Urol Nephrol. 2020 Jul;52(7):1271-1277. doi: 10.1007/s11255-020-02407-z. Epub 2020 Feb 25.
The aim of this study was to summarize in a literature review our treatment experience involving microscopic replantation in a rare case of a completely amputated penis and testes.
The penis and testes were completely amputated due to self-mutilation. The 26-year-old patient immediately underwent microscopic replantation of the penis and testes after pre-operative preparation. Potent anti-infectives and anti-depressives, and microcirculation-improving hyperbaric oxygen therapy were utilized after surgery.
The time between the amputation and surgery was about 10 h. The patient was followed for 12 months post-surgery. The replanted penis recovered and the patient could urinate normally in the standing position with a maximal urinary flow rate of 20 ml/s. The testes also survived, but their size showed obvious atrophy. The serum testosterone level at 2 months after the operation was 120 ng/dL (normal reference range: 175-781 ng/dL). Erectile function gradually recovered after androgen replacement therapy.
Complete amputation of the penis and testis is very rare. Efforts should be made to perform the replantation surgery as soon as possible. Microscopic surgical techniques for elaborate vascular and neural anastomosis constitute the basis for a successful replantation. Post-operative comprehensive treatment such as strong anti-infection, analgesia, anti-depression, improvement of microcirculation, and hyperbaric oxygen is crucial for the survival and functional recovery of replanted organs.
本研究旨在通过文献回顾总结我们在一例罕见完全离断阴茎和睾丸的显微镜再植治疗经验,并进行测试。
患者因自残导致阴茎和睾丸完全离断,在术前准备后,立即对 26 岁患者进行阴茎和睾丸显微镜再植。术后使用强效抗感染、抗抑郁药物及改善微循环的高压氧治疗。
离断至手术的时间约为 10 小时。术后随访 12 个月。再植的阴茎恢复,患者可站立排尿,最大尿流率为 20ml/s。睾丸也存活,但体积明显萎缩。术后 2 个月血清睾酮水平为 120ng/dL(正常参考范围:175-781ng/dL)。雄激素替代治疗后,勃起功能逐渐恢复。
阴茎和睾丸完全离断非常罕见,应尽快进行再植手术。精细的血管和神经吻合显微外科技术是成功再植的基础。术后综合治疗如强力抗感染、镇痛、抗抑郁、改善微循环和高压氧治疗对于再植器官的存活和功能恢复至关重要。