Department of Ophthalmology and Visual Science, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Department of Ophthalmology and Visual Sciences, West Virginia University, Morgantown, WV, USA.
Cutan Ocul Toxicol. 2020 Jun;39(2):122-125. doi: 10.1080/15569527.2020.1734817. Epub 2020 Mar 31.
To compare the incidence of pseudophakic cystoid macular oedema (CME) in patients who receive intracameral cephalosporin versus intracameral vancomycin during cataract surgery. A retrospective chart review was conducted on subjects with the diagnosis of CME between January 1 2010 and July 31 2017. Inclusion criterion was the documentation of CME after cataract extraction. Exclusion criteria were intraoperative complication, prior history of macular oedema, epiretinal membrane, uveitis, other pre-existing retinal pathology, or other post-operative pathology including other ocular surgery in the post-operative period. The final analysis included 89 eyes with optical coherence tomography (OCT) proven CME. The incidence of pseudophakic CME in our population of 10,165 cataract surgeries after applying the above-stated exclusion criteria was 0.88%. The incidence of pseudophakic CME in subjects who received intracameral cephalosporin was 0.87% (mean age in years 69 ± 11; 31 male [39%], 48 female [61%]). The incidence of pseudophakic CME in subjects who received intracameral vancomycin was 0.96% (mean age in years 66 ± 13; 4 male [40%], 6 female [60%]). Pearson's chi-square test demonstrated no significant difference between these groups ( = 0.7705). There was no statistical difference in the incidence of pseudophakic CME in subjects who received intracameral cephalosporin versus intracameral vancomycin during cataract surgery.
比较白内障手术后接受玻璃体内头孢菌素与玻璃体内万古霉素的患者中假性囊泡性黄斑水肿（CME）的发生率。对 2010 年 1 月 1 日至 2017 年 7 月 31 日期间诊断为 CME 的患者进行回顾性图表审查。纳入标准为白内障摘除术后有 CME 记录。排除标准为术中并发症、既往黄斑水肿、视网膜内膜、葡萄膜炎、其他预先存在的视网膜病变或其他术后病理，包括术后期间的其他眼部手术。最终分析包括 89 只经光学相干断层扫描（OCT）证实的 CME 眼。在应用上述排除标准后，我们在 10165 例白内障手术患者中，假性囊泡性 CME 的发生率为 0.88%。接受玻璃体内头孢菌素的患者中假性囊泡性 CME 的发生率为 0.87%（平均年龄为 69±11 岁；31 名男性[39%]，48 名女性[61%]）。接受玻璃体内万古霉素的患者中假性囊泡性 CME 的发生率为 0.96%（平均年龄为 66±13 岁；4 名男性[40%]，6 名女性[60%]）。Pearson's 卡方检验显示两组之间无显著差异（ = 0.7705）。白内障手术后接受玻璃体内头孢菌素与玻璃体内万古霉素的患者中假性囊泡性 CME 的发生率无统计学差异。
