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优化合并哮喘和肥胖的成年患者的生活方式干预措施。

Optimizing lifestyle interventions in adult patients with comorbid asthma and obesity.

机构信息

Department of Allergy and Immunology, Cleveland Clinic, Cleveland, OH, USA.

Division of Pulmonary, Critical Care, Sleep and Allergy, Affiliate Faculty, Center for Dissemination and Implementation Science, University of Illinois at Chicago, 840 S. Wood St. MC 719, Chicago, IL 60612, USA.

出版信息

Ther Adv Respir Dis. 2020 Jan-Dec;14:1753466620906323. doi: 10.1177/1753466620906323.

Abstract

The prevalence of obesity and asthma are both increasing at alarming rates. The link between obesity and asthma suggests that obesity contributes to both risk of new onset asthma and increased asthma severity. The emerging evidence demonstrating the role of obesity and other lifestyle factors, such as diet and physical activity, on asthma outcomes warrants lifestyle interventions that can address these components of asthma care. This review examines the current literature on the pathophysiology of obesity's role in asthma, as well as the role of diet and physical activity in weight loss and in asthma outcomes. We discuss recent studies that employ lifestyle interventions to target improved asthma outcomes. Finally, we discuss the future direction of research in this area. .

摘要

肥胖症和哮喘的患病率都在以惊人的速度增长。肥胖症和哮喘之间的关联表明,肥胖症既会导致新发生的哮喘风险增加,也会导致哮喘严重程度增加。越来越多的证据表明,肥胖症和其他生活方式因素(如饮食和体育活动)在哮喘结局方面发挥作用,这就需要采取生活方式干预措施来解决哮喘治疗的这些方面。这篇综述检查了肥胖症在哮喘中的病理生理学作用以及饮食和体育活动在减肥和哮喘结局方面的作用的现有文献。我们讨论了最近采用生活方式干预措施来改善哮喘结局的研究。最后,我们讨论了该领域未来的研究方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48fb/7047422/adee69f3d07d/10.1177_1753466620906323-fig1.jpg

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