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青年环状苔藓样皮炎——环孢素治疗罕见皮肤病复发病例

Annular lichenoid dermatitis of youth-Recurrent case of rare skin disease treated with cyclosporine.

作者信息

Stojkovic-Filipovic Jelena, Lekic Branislav, Brasanac Dimitrije, Lalosevic Jovan, Gajic-Veljic Mirjana, Nikolic Milos

机构信息

School of Medicine, University of Belgrade, Belgrade, Serbia.

Clinic of Dermatovenereology, Clinical Center of Serbia, Belgrade, Serbia.

出版信息

Dermatol Ther. 2020 May;33(3):e13285. doi: 10.1111/dth.13285. Epub 2020 Mar 26.

DOI:10.1111/dth.13285
PMID:32105384
Abstract

Annular lichenoid dermatitis of youth (ALDY), first described in 2003, represents an uncommon entity whose etiopathogenesis is still debated. Futhermore, the optimal treatment for ALDY is yet to be established. We report a 9-year-old girl who presented with annular and oval erythematous lesions mostly on her trunk, with several lesions on the neck, groin, flanks, and upper extremities. The lesions had histological and immunohistochemical features characteristic for ALDY. Treatment with H1-antihistamines, topical corticosteroid, and UVB therapy was unsuccessful, while systemic treatment with cyclosporine induced complete remission.

摘要

青年环状苔藓样皮炎(ALDY)于2003年首次被描述,是一种病因仍存在争议的罕见疾病。此外,ALDY的最佳治疗方法尚未确定。我们报告一名9岁女孩,其躯干出现环形和椭圆形红斑性皮损,颈部、腹股沟、侧腹和上肢也有多处皮损。这些皮损具有ALDY的组织学和免疫组化特征。使用H1抗组胺药、外用糖皮质激素和紫外线B光疗均无效,而环孢素全身治疗诱导了完全缓解。

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