Department of Health Policy and Management, School of Public Health, Fudan University, Shanghai, China.
The 3rd People's Hospital of Xiangcheng District, Suzhou, China.
PLoS One. 2020 Feb 27;15(2):e0229652. doi: 10.1371/journal.pone.0229652. eCollection 2020.
Although older diabetes patients with unique characteristics should be cared carefully to improve their health-related quality of life (HRQOL), the association between diabetes and HRQOL remain unclear, especially in Asians. We aimed to compare the HRQOL between older Chinese patients with type 2 diabetes (T2D) and their age-gender-matched controls.
Older patients with T2D were recruited from a community hospital in Suzhou located in the east part of China while controls were selected from a community-based health survey of older adults aged 60 years or older. HRQOL of cases and controls was assessed by the EQ-5D-3L. The impact of T2D on HRQOL was investigated using a liner regression model and the relationship between T2D and EQ-5D health problems was evaluated using logistic regression models.
A total of 220 cases and 440 controls were included. The mean age of the participants was 68.8 years and women accounted for 69.1% of the study sample. The EQ-5D-3L index score was lower for older people with T2D (0.886) than their controls (0.955). After multivariable adjustment, the difference in ED-5D-3L index score between older people with and without T2D was 0.072. In logistic regression analyses, T2D was positively associated with reporting of problems in mobility (odds ratio [OR] = 5.00); pain/discomfort (OR = 1.66), and anxiety/depression (OR = 3.2).
T2D has a detrimental effect on HRQOL of older Chinese people.
尽管具有独特特征的老年糖尿病患者需要精心护理以提高其健康相关生活质量(HRQOL),但糖尿病与 HRQOL 之间的关系仍不清楚,尤其是在亚洲人群中。我们旨在比较中国东部苏州市社区医院就诊的老年 2 型糖尿病(T2D)患者与年龄、性别相匹配的对照组之间的 HRQOL。
T2D 老年患者从中国东部苏州市的一家社区医院招募,而对照组则从一项针对 60 岁及以上老年人的社区基础健康调查中选择。采用 EQ-5D-3L 量表评估病例和对照组的 HRQOL。使用线性回归模型探讨 T2D 对 HRQOL 的影响,使用逻辑回归模型评估 T2D 与 EQ-5D 健康问题之间的关系。
共纳入 220 例病例和 440 例对照。参与者的平均年龄为 68.8 岁,女性占研究样本的 69.1%。T2D 老年患者的 EQ-5D-3L 量表指数评分(0.886)低于其对照组(0.955)。多变量调整后,T2D 老年患者与无 T2D 老年患者的 EQ-5D-3L 指数评分差异为 0.072。在逻辑回归分析中,T2D 与报告的行动不便(优势比[OR] = 5.00)、疼痛/不适(OR = 1.66)和焦虑/抑郁(OR = 3.2)呈正相关。
T2D 对中国老年人群的 HRQOL 有不利影响。