Department of Orthopaedics, Uzsoki Hospital, Uzsoki street 29, Budapest 1145, Hungary.
Department of Traumatology, Semmelweis University, Budapest, Hungary.
Injury. 2021 Mar;52 Suppl 1:S53-S56. doi: 10.1016/j.injury.2020.02.054. Epub 2020 Feb 16.
The surgical, arthroscopic synovectomy and radiosynovectomy (radiosynoviorthesis, RSO) all have great practical importance, since they can eliminate the posttraumatic joint bleedings and prevent the further joint destructions in hemophilic patients. The aim of this study was to examine the role of RSO in the prevention of joint bleedings in hemophilic patients.
54 out of 684 RSO patients were hemophiliacs. Mean age of the patients was 32 years (range 14-51), therefore this is a relatively young patients' cohort. Radiosynovectomy was performed in 37 patients with hemophilia A and in 17 patients suffering from hemophilia B. Since hemophilia is a sex-linked (x-linked) recessive disorder, all of the patients were male. There was no acquired hemophiliac among the treated patients.
The RSO resulted in a 95% decline in bleedings per year and eliminated the incidence of further bleedings in 55% of the treated joints.
Our findings support the view that radiosynoviorthesis can be considered as the first choice treatment for posttraumatic joint bleedings of hemophilic patients.
关节镜下滑膜切除术和放射性滑膜切除术（放射性滑膜切开术，RSO）都具有重要的实际意义，因为它们可以消除血友病患者的创伤后关节出血，并防止进一步的关节破坏。本研究旨在探讨 RSO 在预防血友病患者关节出血中的作用。
684 例 RSO 患者中有 54 例为血友病患者。患者的平均年龄为 32 岁（范围 14-51 岁），因此这是一个相对年轻的患者群体。37 例血友病 A 患者和 17 例血友病 B 患者接受了放射性滑膜切除术。由于血友病是一种伴性（X 连锁）隐性遗传病，所有患者均为男性。在接受治疗的患者中没有获得性血友病患者。
RSO 使每年的出血减少了 95%，并使 55%的治疗关节不再发生进一步出血。
我们的研究结果支持这样一种观点，即放射性滑膜切开术可以被视为血友病患者创伤后关节出血的首选治疗方法。
