Department Surgery, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
Am J Otolaryngol. 2020 Nov-Dec;41(6):102413. doi: 10.1016/j.amjoto.2020.102413. Epub 2020 Feb 11.
Intrathecal fluorescein is commonly used to localize cerebrospinal fluid leaks. This technique is invasive and associated with several potential adverse effects. The purpose of this video presentation is to demonstrate an alternative technique, the intranasal use of dilute topical fluorescein, to localize a cerebrospinal fluid leak intraoperatively.
A 45-year-old male with a history of benign intracranial hypertension and 2 months of right-sided rhinorrhea underwent surgical repair of a cerebrospinal fluid leak. Topical fluorescein was applied intraoperatively to localize the defect.
At 1- and 3-month follow-ups the patient was without cerebrospinal fluid rhinorrhea and the middle turbinate flap was intact.
Topical application of dilute intranasal fluorescein is a feasible and efficient tool for localizing cerebrospinal fluid leaks.
鞘内荧光素常用于定位脑脊液漏。该技术具有侵入性，且与多种潜在的不良反应相关。本视频演示的目的是介绍一种替代技术，即经鼻使用稀释的局部荧光素，以在术中定位脑脊液漏。
一名 45 岁男性，有颅内良性高压病史，右侧鼻漏 2 个月，接受了脑脊液漏的手术修复。术中应用局部荧光素定位缺陷。
在 1 个月和 3 个月的随访中，患者无脑脊液鼻漏，中鼻甲瓣完整。
经鼻应用稀释的局部荧光素是一种可行且有效的定位脑脊液漏的工具。
