Department of Ultrasound, Peking University Third Hospital, Beijing 100191, China.
Department of Ultrasound, Peking University Third Hospital, Beijing 100191, China.
Ultrasound Med Biol. 2020 May;46(5):1197-1207. doi: 10.1016/j.ultrasmedbio.2020.01.017. Epub 2020 Feb 24.
The 3 Tesla (3T) magnetic resonance imaging (MRI) combined ultrasound (TRUS) targeted biopsy plus 12-core systematic biopsy (TBx + 12-SBx) was considered a reliable method for prostate cancer (PCa) diagnosis. To find another optimal sampling scheme with fewer cores and the same efficiency as TBx + 12-SBx for prostate biopsy, 113 patients who underwent five different hypothetical sampling schemes were analyzed and compared with TBx + 12-SBx. The detection rates of targeted biopsy plus 6-core lateral systematic biopsy (TBx + lateral 6-SBx) for PCa and clinically significant prostate cancer (csPCa) (99.1% and 96.4%, respectively) were higher than other schemes, and the area under the receiver operating characteristic curve of TBx + lateral 6-SBx for PCa and csPCa (0.991 and 0.990, respectively) were also significantly higher than other sampling schemes except TBx plus 6-core ipsilateral systematic biopsy (TBx + ipsilateral 6-SBx). Additionally, TBx + lateral 6-SBx had the lowest missed diagnosis rate. Thus, the TBx + lateral 6-SBx may be the optimal scheme for patients undergoing MRI/TRUS fusion prostate biopsy.
3 特斯拉（3T）磁共振成像（MRI）联合超声（TRUS）靶向活检加 12 芯系统活检（TBx+12-SBx）被认为是前列腺癌（PCa）诊断的可靠方法。为了找到另一种优化的取样方案，用更少的核心和与 TBx+12-SBx 相同的效率进行前列腺活检，对 113 名接受 5 种不同假设取样方案的患者进行了分析，并与 TBx+12-SBx 进行了比较。靶向活检加 6 芯侧系统活检（TBx+ lateral 6-SBx）对 PCa 和临床显著前列腺癌（csPCa）的检出率（分别为 99.1%和 96.4%）高于其他方案，TBx+ lateral 6-SBx 对 PCa 和 csPCa 的受试者工作特征曲线下面积（分别为 0.991 和 0.990）也显著高于其他取样方案，除了 TBx 加 6 芯对侧系统活检（TBx+ipsilateral 6-SBx）。此外，TBx+ lateral 6-SBx 的漏诊率最低。因此，TBx+ lateral 6-SBx 可能是接受 MRI/TRUS 融合前列腺活检的患者的最佳方案。
