Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Ultrasound Med Biol. 2020 May;46(5):1158-1168. doi: 10.1016/j.ultrasmedbio.2020.01.020. Epub 2020 Feb 24.
The aims of this study were to explore the long-term impact of pericardiectomy on left atrial (LA) functions in patients with constrictive pericarditis (CP) using speckle tracking echocardiography (STE) and to correlate post-operative LA functions with clinical status. Echocardiographic examinations were undertaken in 29 patients with CP 1 wk before and 1, 6 and 12 mo after pericardiectomy. STE was performed to obtain LA global longitudinal strain, including strain during the conduit phase (LAScd), strain during the contraction phase (LASct) the sum of the latter and strain during the reservoir phase (LASr). Control patients consisted of 29 age- and sex-matched healthy volunteers. LASct, LAScd and LASr obtained 6 mo after pericardiectomy improved significantly compared with pre-operative values, but were still lower than the values for control patients. Further increases were observed gradually with normalization of LASct 12 mo after pericardiectomy. However, there were still significant differences between LAScd and LASr obtained in control patients and those obtained 12 mo after pericardiectomy. Moreover, the improvements in LAScd, LASct and LASr 12 mo after pericardiectomy correlated well with symptomatic clinical alleviation (p < 0.01). These results indicate that LA strains analyzed with STE might be useful in evaluating the long-term impact of pericardiectomy on LA functions.
本研究旨在应用斑点追踪超声心动图（STE）探讨心包剥离术对缩窄性心包炎（CP）患者左心房（LA）功能的长期影响，并分析术后 LA 功能与临床状态的相关性。29 例 CP 患者于心包剥离术前 1 周及术后 1、6、12 个月行超声心动图检查。STE 用于获取 LA 整体纵向应变，包括管道期应变（LAScd）、收缩期应变（LASct）及两者之和（LASr）。对照组为 29 名年龄、性别匹配的健康志愿者。与术前值相比，术后 6 个月时 LASct、LAScd 和 LASr 明显改善，但仍低于对照组。术后 12 个月时，LASct 逐渐恢复正常，进一步增加。然而，对照组与心包剥离术后 12 个月时的 LAScd 和 LASr 仍存在显著差异。此外，心包剥离术后 12 个月时 LAScd、LASct 和 LASr 的改善与症状缓解程度显著相关（p<0.01）。这些结果表明，STE 分析的 LA 应变可能有助于评估心包剥离术对 LA 功能的长期影响。
