Department of Intensive Care, Austin Hospital, Melbourne, VIC, Australia.
Adult Critical Care, Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom.
Crit Care Med. 2020 May;48(5):717-724. doi: 10.1097/CCM.0000000000004284.
To compare the characteristics of adults admitted to the ICU in Australia and New Zealand after trauma with nonelective, nontrauma admissions. To describe trends in hospital mortality and rates of discharge home among these two groups.
Retrospective review (2005-2017) of the Australia and New Zealand Intensive Care Society's Center for Outcome and Resource Evaluation Adult Patient Database.
Adult ICUs in Australia and New Zealand.
Adult (≥17 yr), nonelective, ICU admissions.
Observational study.
We compared 77,002 trauma with 741,829 nonelective, nontrauma patients. Trauma patients were younger (49.0 ± 21.6 vs 60.6 ± 18.7 yr; p < 0.0001), predominantly male (73.1% vs 53.9%; p < 0.0001), and more frequently treated in tertiary hospitals (74.7% vs 45.8%; p < 0.0001). The mean age of trauma patients increased over time but was virtually static for nonelective, nontrauma patients (0.72 ± 0.02 yr/yr vs 0.03 ± 0.01 yr/yr; p < 0.0001). Illness severity increased for trauma but fell for nonelective, nontrauma patients (mean Australia and New Zealand risk of death: 0.10% ± 0.02%/yr vs -0.21% ± 0.01%/yr; p < 0.0001). Trauma patients had a lower hospital mortality than nonelective, nontrauma patients (10.0% vs 15.8%; p < 0.0001). Both groups showed an annual decline in the illness severity adjusted odds ratio (odds ratio) of hospital mortality, but this was slower among trauma patients (trauma: odds ratio 0.976/yr [0.968-0.984/yr; p < 0.0001]; nonelective, nontrauma: odds ratio 0.957/yr [0.955-0.959/yr; p < 0.0001]; interaction p < 0.0001). Trauma patients had lower rates of discharge home than nonelective, nontrauma patients (56.7% vs 64.6%; p < 0.0001). There was an annual decline in illness severity adjusted odds ratio of discharge home among trauma patients, whereas nonelective, nontrauma patients displayed an annual increase (trauma: odds ratio 0.986/yr [0.981-0.990/yr; p < 0.0001]; nonelective, nontrauma: odds ratio 1.014/yr [1.012-1.016/yr; p < 0.0001]; interaction: p < 0.0001).
The age and illness severity of adult ICU trauma patients in Australia and New Zealand has increased over time. Hospital mortality is lower for trauma than other nonelective ICU patients but has fallen more slowly. Trauma patients have become less likely to be discharged home than other nonelective ICU patients.
比较澳大利亚和新西兰创伤后和非创伤性、非择期 ICU 成人入住患者的特征。描述这两组患者的医院死亡率和出院回家率的趋势。
澳大利亚和新西兰重症监护学会中心的回顾性研究(2005-2017 年),对结果和资源评估成人患者数据库进行回顾。
澳大利亚和新西兰的成人 ICU。
成人(≥17 岁),非择期 ICU 入住患者。
观察性研究。
我们比较了 77002 例创伤患者和 741829 例非创伤、非择期患者。创伤患者年龄更小(49.0±21.6 岁 vs 60.6±18.7 岁;p<0.0001),主要为男性(73.1% vs 53.9%;p<0.0001),更多地在三级医院接受治疗(74.7% vs 45.8%;p<0.0001)。创伤患者的平均年龄随时间增加,但对于非创伤、非择期患者则基本不变(0.72±0.02 岁/年 vs 0.03±0.01 岁/年;p<0.0001)。创伤患者的疾病严重程度增加,但非创伤、非择期患者的疾病严重程度下降(澳大利亚和新西兰的平均风险:0.10%±0.02%/年 vs -0.21%±0.01%/年;p<0.0001)。创伤患者的医院死亡率低于非创伤、非择期患者(10.0% vs 15.8%;p<0.0001)。两组患者的疾病严重程度调整后的医院死亡率比值比(OR)均呈每年下降趋势,但创伤患者的下降速度较慢(创伤:OR 0.976/年[0.968-0.984/年;p<0.0001];非创伤、非择期:OR 0.957/年[0.955-0.959/年;p<0.0001];交互作用 p<0.0001)。创伤患者出院回家的比例低于非创伤、非择期患者(56.7% vs 64.6%;p<0.0001)。创伤患者的疾病严重程度调整后的出院回家 OR 呈每年下降趋势,而非创伤、非择期患者则呈每年上升趋势(创伤:OR 0.986/年[0.981-0.990/年;p<0.0001];非创伤、非择期:OR 1.014/年[1.012-1.016/年;p<0.0001];交互作用:p<0.0001)。
澳大利亚和新西兰创伤后 ICU 成人患者的年龄和疾病严重程度随时间增加而增加。创伤患者的医院死亡率低于其他非择期 ICU 患者,但下降速度较慢。创伤患者出院回家的可能性低于其他非择期 ICU 患者。