Ni Zhimin, Sun Jiachen, Qi Shiling
The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Department of Gastrointestinal Endoscopy, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Surg Infect (Larchmt). 2020 Oct;21(8):722-725. doi: 10.1089/sur.2019.184. Epub 2020 Feb 28.
To evaluate the efficacy and safety of topical negative pressure therapy/vacuum-associated closure (TPN/VAC) in the treatment of cephalic facial skin abscess with infection. Forty-seven patients with cephalic facial skin abscesses were divided into two groups. The observation group was treated with negative pressure sealing drainage technique and primary wound suture. The control group was treated with abscess incision and drainage first; the second stage was wound suture after three to five days. The time and times of wound dressing, the pain score during wound dressing, the time of antibiotic use, and the recurrence rate were observed. The wound healing time of the observation group was seven days, which was better than that of the control group for 10-12 days. The time of dressing change in the observation group was 14.9 ± 2.0 minutes (11-19 minutes), and the time of dressing change in the control group was 14.6 ± 2.6 minutes (10-20 minutes). There was no difference between the two groups (p > 0.05). The total number of dressing changes per patient in the observation group was three to five times, and the total number of dressing changes per patient in the observation group was five to eight times. There was a statistically significant difference between the two groups (p < 0.05). The pain score of the observation group was 3.2 ± 0.6 points (2-4 points), and the pain score of the control group was 5.1 ± 0.8 points (4-7 points). The difference between the two groups was statistically significant (p < 0.05). There was no recurrence in the observation group and two cases in the control group. Local negative pressure closed drainage technology can shorten the patient's healing course and reduce the duration of treatment, reduce the pain of dressing changes, improve prognosis, and have satisfactory therapeutic effect. It is a simple, effective, and safe technology, which is worthy of clinical application.
评估局部负压疗法/封闭负压引流术（TPN/VAC）治疗头面部皮肤脓肿伴感染的疗效及安全性。将47名头面部皮肤脓肿患者分为两组。观察组采用负压封闭引流技术并一期伤口缝合。对照组先行脓肿切开引流；二期在3至5天后行伤口缝合。观察伤口换药时间及次数、换药时疼痛评分、抗生素使用时间及复发率。观察组伤口愈合时间为7天，优于对照组的10至12天。观察组换药时间为14.9±2.0分钟（11至19分钟），对照组换药时间为14.6±2.6分钟（10至20分钟）。两组间无差异（p＞0.05）。观察组患者每人换药总次数为3至5次，对照组患者每人换药总次数为5至8次。两组间差异有统计学意义（p＜0.05）。观察组疼痛评分为3.2±0.6分（2至4分），对照组疼痛评分为5.1±0.8分（4至7分）。两组间差异有统计学意义（p＜0.05）。观察组无复发，对照组有2例复发。局部负压封闭引流技术可缩短患者愈合疗程，减少治疗时间，减轻换药疼痛，改善预后，治疗效果满意。是一种简单、有效、安全的技术，值得临床应用。
