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一名14岁女孩患非放射学轴向脊柱关节炎，表现为肌肉无力和甲状腺功能亢进症的病例。

A Case of a Non-Radiographic Axial Spondyloarthritis in a 14-Year-Old Girl Presenting with Muscle Weakness and Hyperthyroidism.

作者信息

Elhosiny Abdullah, Alshoubaki Renad, Sindi Lama, Bukhari Sadeem, Almoallim Hani

机构信息

Department of Medicine, Dr. Soliman Fakeeh Hospital, Jeddah, Saudi Arabia.

Department of Medicine, Faculty of Medicine, Umm Alqura University, Makkah, Saudi Arabia.

出版信息

Int Med Case Rep J. 2020 Feb 20;13:47-52. doi: 10.2147/IMCRJ.S233427. eCollection 2020.

DOI:10.2147/IMCRJ.S233427
PMID:32110118
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7039058/
Abstract

Juvenile spondyloarthritis (SpA) affects patients below the age of 16 and mainly presents with peripheral involvement. Many atypical clinical presentations were reported in the adult SpA, but not in the juvenile group. We report a case of non-radiographic axial SpA in a 14-year-old girl presented atypically with muscle weakness and hyperthyroidism. She had sacroiliitis evident by magnetic resonance imaging (MRI) with negative HLA-B27. Muscle biopsy showed fasciitis. She responded well to adalimumab and thyroid functions returned to normal values.

摘要

青少年脊柱关节炎（SpA）影响16岁以下的患者，主要表现为外周关节受累。成人SpA有许多非典型临床表现的报道，但青少年组未见此类报道。我们报告一例14岁女孩的非放射学中轴型SpA，其表现不典型，有肌肉无力和甲状腺功能亢进。磁共振成像（MRI）显示她有骶髂关节炎，HLA-B27阴性。肌肉活检显示为筋膜炎。她对阿达木单抗反应良好，甲状腺功能恢复到正常水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/164e/7039058/3cadbea9495b/IMCRJ-13-47-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/164e/7039058/d37f84725abe/IMCRJ-13-47-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/164e/7039058/832384784a16/IMCRJ-13-47-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/164e/7039058/3cadbea9495b/IMCRJ-13-47-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/164e/7039058/d37f84725abe/IMCRJ-13-47-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/164e/7039058/832384784a16/IMCRJ-13-47-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/164e/7039058/3cadbea9495b/IMCRJ-13-47-g0003.jpg

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本文引用的文献

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Fever as an initial manifestation of spondyloarthritis: A retrospective study.发热作为脊柱关节炎的初始表现：一项回顾性研究。
PLoS One. 2017 Sep 14;12(9):e0184323. doi: 10.1371/journal.pone.0184323. eCollection 2017.
2
Efficacy of TNFα blockers in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: a meta-analysis.TNFα 阻滞剂在强直性脊柱炎和非影像学轴性脊柱关节炎患者中的疗效：一项荟萃分析。
Ann Rheum Dis. 2015 Jun;74(6):1241-8. doi: 10.1136/annrheumdis-2014-205322. Epub 2014 Apr 9.
3
Autoimmune thyroid disease in ankylosing spondylitis.
强直性脊柱炎中的自身免疫性甲状腺疾病。
Clin Rheumatol. 2014 Jul;33(7):955-61. doi: 10.1007/s10067-013-2466-1. Epub 2014 Jan 3.
4
Inflammatory myopathy with abundant macrophages (IMAM): the immunology revisited.富含巨噬细胞的炎性肌病（IMAM）：免疫学分型再探讨。
Neuromuscul Disord. 2014 Feb;24(2):151-5. doi: 10.1016/j.nmd.2013.11.004. Epub 2013 Nov 18.
5
Clinical and radiological presentations of late-onset spondyloarthritis.迟发性脊柱关节炎的临床和影像学表现。
ISRN Rheumatol. 2011;2011:840475. doi: 10.5402/2011/840475. Epub 2011 Mar 20.
6
Rheumatic manifestations of endocrine disease.内分泌疾病的风湿表现。
Curr Opin Rheumatol. 2013 Jan;25(1):37-43. doi: 10.1097/BOR.0b013e32835b4f3f.
7
Thyroid involvement in ankylosing spondylitis and relationship of thyroid dysfunction with anti-TNF α treatment.强直性脊柱炎的甲状腺受累及甲状腺功能障碍与抗 TNF-α治疗的关系。
Rheumatol Int. 2013 Apr;33(4):853-7. doi: 10.1007/s00296-012-2438-9. Epub 2012 May 22.
8
Spondyloarthropathies in autoimmune diseases and vice versa.自身免疫性疾病中的脊柱关节病，反之亦然。
Autoimmune Dis. 2012;2012:736384. doi: 10.1155/2012/736384. Epub 2012 Feb 15.
9
Prevalence of thyroid autoimmunity in patients with spondyloarthropathies.脊柱关节炎患者甲状腺自身免疫的流行情况。
J Rheumatol. 2011 Jul;38(7):1371-7. doi: 10.3899/jrheum.101012. Epub 2011 Apr 15.
10
Aortitis and spondyloarthritis--an unusual presentation: case report and review of the literature.巨细胞动脉炎和脊柱关节炎——一种不常见的表现：病例报告及文献复习。
Semin Arthritis Rheum. 2010 Jun;39(6):510-4. doi: 10.1016/j.semarthrit.2008.11.004. Epub 2009 Feb 13.