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尼泊尔上呼吸道感染抗生素广告与治疗可及性公平性:一项横断面研究

Advertisement of antibiotics for upper respiratory infections and equity in access to treatment: a cross-sectional study in Nepal.

作者信息

Koju Pramesh, Rousseau Stéphane P, Van der Putten Marc, Shrestha Archana, Shrestha Rajeev

机构信息

1Dhulikhel Hospital, Kathmandu University Hospital, Dhulikhel, PO Box 11008, Kathmandu, Nepal.

2School of Global Studies, Thammasat University, Bangkok, Thailand.

出版信息

J Pharm Policy Pract. 2020 Feb 21;13:4. doi: 10.1186/s40545-020-0202-1. eCollection 2020.

Abstract

BACKGROUND

Pharmaceutical companies actively advertise their branded antibiotics, which influence their sales at community pharmacies. The major proportion of out of pocket health spending is on medicine; and affordability of antibiotics has always been a crucial issue in most developing countries. This study identified promotional activities adopted by pharmaceutical companies in community pharmacies and medicine shops and the affordability of selected antibiotics to clients with lowest wages in Kavrepalanchok district of Nepal.

METHODS

A cross-sectional study was conducted among all community pharmacies and medicine shops ( = 34) in Dhulikhel and Banepa. Available pharmacists / personnel were interviewed, using a structured questionnaire, on the characteristics of the pharmacies, promotional activities, and sales and prices of antibiotics used to treat acute upper respiratory tract infections. This study looked at the association of promotional activities (financial bonus, free samples, and books/brochure/gifts) with the type of antibiotics. Further, affordability was assessed of the most popular antibiotics by comparing the total treatment cost against the lowest wage for unskilled workers in Nepal.

RESULTS

Financial bonus, free samples, and brochures were the most popular promotional activities. It is also noticed that antibiotics which are top selling were those with a high number of promotional activities. Amoxicillin, azithromycin and amoxicillin+clavulanate had 42, 29 and 17 promotional activities respectively. Irrespective of the prices of antibiotics, almost all of the most popular antibiotics for acute upper respiratory infections were unaffordable for unskilled workers costing them more than a day's wage.

CONCLUSIONS

Upper respiratory tract antibiotics are widely promoted at community pharmacies. The treatment cost of antibiotics is unaffordable for unskilled workers in Nepal irrespective of the type and unit cost of antibiotics.

摘要

背景

制药公司积极宣传其品牌抗生素,这影响了它们在社区药房的销售。自费医疗支出的主要部分用于药品;在大多数发展中国家,抗生素的可负担性一直是一个关键问题。本研究确定了制药公司在社区药房和药店开展的促销活动,以及尼泊尔卡夫雷帕兰乔克地区工资最低的客户购买特定抗生素的可负担性。

方法

在杜利凯尔和巴内帕的所有社区药房和药店(共34家)开展了一项横断面研究。使用结构化问卷对在岗药剂师/工作人员进行访谈,了解药房的特点、促销活动以及用于治疗急性上呼吸道感染的抗生素的销售和价格情况。本研究考察了促销活动(经济奖励、免费样品以及书籍/手册/礼品)与抗生素类型之间的关联。此外,通过将总治疗成本与尼泊尔非技术工人的最低工资进行比较,评估了最常用抗生素的可负担性。

结果

经济奖励、免费样品和手册是最受欢迎的促销活动。还注意到,促销活动次数多的抗生素销量最高。阿莫西林、阿奇霉素和阿莫西林+克拉维酸分别有42次、29次和17次促销活动。无论抗生素价格如何,几乎所有用于急性上呼吸道感染的最常用抗生素对于非技术工人来说都难以负担,花费超过了他们一天的工资。

结论

社区药房广泛推广上呼吸道感染用抗生素。在尼泊尔,无论抗生素的类型和单位成本如何,非技术工人都难以负担抗生素的治疗费用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2198/7033932/17d393e1c4cd/40545_2020_202_Fig1_HTML.jpg

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