Mathew Mebin George, Soni Ashu Jagdish, Khan Md Muzammil, Kauser Afreen
Department of Pedodontics and Preventive Dentistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India.
Department of Pediatric Dentistry, Dr. Ashu's Dental Clinic, Vadodara, Gujarat, India.
J Family Med Prim Care. 2020 Jan 28;9(1):428-431. doi: 10.4103/jfmpc.jfmpc_919_19. eCollection 2020 Jan.
Destructive periodontal diseases are rare occurrences in the paediatric population. Moreover, the regenerative potential of the periodontal tissues and supporting structures of teeth is even rare, once irreversible damage has occurred. The aim of this paper is to discuss the regeneration of alveolar bone defect in a 14-year-old using concentrated growth factors (CGF). Following crown removal, scaling, debridement and site preparation, CGF was placed and secured in one-walled defect in the mesial side of the lower right permanent molar. The crown was replaced on to the tooth and the patient was followed up at 1, 3, 6, 9 and 12 months for clinical and radiographic evaluation. After 12 months, the radiographic evaluation revealed the defect to be filled with alveolar bone and probing pocket depth had reduced significantly. Thus, CGF can be an effective agent and can act as a potential scaffold for periodontal regeneration in adolescents with bone loss.
破坏性牙周疾病在儿童群体中较为罕见。此外，一旦发生不可逆损伤，牙周组织和牙齿支持结构的再生潜力更是微乎其微。本文旨在探讨使用浓缩生长因子（CGF）对一名14岁患者的牙槽骨缺损进行再生治疗。在去除牙冠、进行洁治、刮治和术区准备后，将CGF放置并固定于右下第一恒磨牙近中侧的单壁缺损处。将牙冠重新安装到牙齿上，并在1、3、6、9和12个月时对患者进行随访，以进行临床和影像学评估。12个月后，影像学评估显示缺损处已被牙槽骨填充，探诊袋深度显著降低。因此，CGF可以成为一种有效的制剂，并可作为青少年骨丧失患者牙周再生的潜在支架材料。
