Aizman Leora, Van Den Anker John, Tender Jennifer, Krishnan Anita, Kirkorian Anna Yasmine
Department of Dermatology, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Division of Clinical Pharmacology, Children's National Hospital, Washington, DC, USA.
Pediatr Dermatol. 2020 May;37(3):537-540. doi: 10.1111/pde.14134. Epub 2020 Feb 28.
Propranolol is approved for treatment of infantile hemangiomas (IH). IH proliferation coincides with the time when most women are breastfeeding, yet there are no reports describing the clinical effects on infants treated with propranolol while being nursed by mothers on oral antihypertensive medications. We describe two cases of breastfed infants, with mothers taking multiple antihypertensives of different drug classes, who were initiated on propranolol for IH treatment and discuss the theoretical risk of propranolol use in this setting.
普萘洛尔被批准用于治疗婴儿血管瘤（IH）。婴儿血管瘤的增殖期与大多数女性哺乳期相重合，但尚无报告描述母亲正在服用口服抗高血压药物时，接受普萘洛尔治疗的婴儿的临床效果。我们描述了两例母乳喂养的婴儿，其母亲服用多种不同类别的抗高血压药物，这两名婴儿开始使用普萘洛尔治疗婴儿血管瘤，并讨论了在这种情况下使用普萘洛尔的理论风险。
