Department of Physical Medicine and Rehabilitation, Kaohsiung Veterans General Hospital, Zuoying District, Kaohsiung 813, Taiwan.
Department of Rehabilitation Medicine, Cishan Hospital Ministry of Health and Welfare, Cishan District, Kaohsiung 84247, Taiwan.
Int J Environ Res Public Health. 2020 Feb 26;17(5):1496. doi: 10.3390/ijerph17051496.
Prader-Willi syndrome (PWS) is a genetic disorder characterized by specific physical and behavioral abnormalities and considered the most commonly known genetic cause of morbid obesity in children. Recent studies indicate that patients suffering from this syndrome have significant problems in skill acquisition, muscle force, cardiovascular fitness, and activity level. In this study, we report an obese adolescent PWS patient of poor aerobic fitness compared with 13 obesity adolescents, and great improvement in cardiopulmonary exercise test (CPET) outcomes of the PWS patient measured after two weeks of physical exercise training programs.
普拉德-威利综合征(PWS)是一种遗传性疾病,其特征为特定的身体和行为异常,被认为是儿童病态肥胖最常见的遗传原因。最近的研究表明,患有这种综合征的患者在技能获取、肌肉力量、心血管健康和活动水平方面存在显著问题。在本研究中,我们报告了一例肥胖的青少年 PWS 患者,其有氧适能较差,与 13 名肥胖青少年相比,该患者在两周的体能训练计划后,心肺运动测试(CPET)的结果有了很大改善。