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不孕不育的解决是否与女性幸福感的改变有关?

Is infertility resolution associated with a change in women's well-being?

机构信息

Human Development and Family Science, Oklahoma State University, Tulsa, OK, USA.

Emeritus of Sociology, Alfred University, Alfred, NY, USA.

出版信息

Hum Reprod. 2020 Mar 27;35(3):605-616. doi: 10.1093/humrep/dez297.

Abstract

STUDY QUESTION

Is giving birth associated with improved subjective well-being among involuntarily childless women?

SUMMARY ANSWER

Resolution of infertility is associated with increased life satisfaction and self-esteem, but not with a decrease in depressive symptoms.

WHAT IS KNOWN ALREADY

Cross-sectional data and studies of treatment-seekers show that infertility is associated with lower subjective well-being. Childless women with infertility tend to report lower subjective well-being than women who experience secondary infertility, but a prospective study using a random sample of involuntarily childless women over time has not previously been conducted.

STUDY DESIGN, SIZE, DURATION: The sample for the current study includes all women without children who met medical criteria for infertility or perceived a fertility problem (N = 283) at baseline and who were interviewed in both waves (3 years apart) of the National Survey of Fertility Barriers (NSFB), in a random-digit dialing telephone survey. It is therefore possible to explore here whether there are differences in the association of infertility resolution and subjective well-being among women who do and do not perceive themselves as having a fertility problem.

PARTICIPANTS/MATERIALS, SETTING, METHODS: Depressive symptoms (as measured by the Center for Epidemiologic Studies-Depression Scale), self-esteem (as measured by a modified version of the Rosenberg Self-esteem Scale) and life satisfaction (as measured by a modified version of the Satisfaction with Life Scale) were assessed for all 283 participants at both waves. For all three variables, change scores of 47 involuntarily childless women who resolved their infertility through a live birth were compared to the scores for the 236 women who remained childless. A number of variables shown to be associated with subjective well-being among infertile women were included as controls.

MAIN RESULTS AND THE ROLE OF CHANCE

No relationship between infertility resolution and change in depressive symptoms was observed (b = -0.04; P > 0.05). Involuntarily childless women who resolved their infertility improved in self-esteem (b = 0.74; P < 0.01) and life satisfaction (b = 1.06; P < 0.01).

LIMITATIONS, REASONS FOR CAUTION: Women were measured at only two time points. Only 47 women had a live birth between waves. While it is common practice to make causal interpretations based on panel data, such interpretations should be made with caution. In addition, the NSFB was conducted in the USA where medical expenditures are high and most fertility treatment expenses are not covered by insurance. Thus it may not be possible to generalize the findings to other modern industrialized societies.

WIDER IMPLICATIONS OF THE FINDINGS

Knowing that resolution of infertility is associated with improved subjective well-being is important for infertile couples and infertility professionals alike.

STUDY FUNDING/COMPETING INTEREST(S): This research was supported in part by NICHD grant R01-HD044144 and NIGMS grant P20-GM109097 from the National Institutes of Health. The authors have no competing interests.

摘要

研究问题

生育是否会提高不孕不育女性的主观幸福感?

总结答案

解决不孕问题与生活满意度和自尊心的提高有关,但与抑郁症状的减轻无关。

已知事实

横断面数据和寻求治疗的研究表明,不孕与较低的主观幸福感有关。与经历继发性不孕的女性相比,不孕的无子女女性往往报告的主观幸福感较低,但以前没有对随时间推移的、来自随机选择的不孕不育女性进行的前瞻性研究。

研究设计、大小和持续时间:当前研究的样本包括所有符合不孕医学标准或感知生育问题的无子女女性(基线时 N=283),并在全国生育障碍调查(NSFB)的两次(相隔 3 年)访谈中进行了采访。因此,这里可以探讨解决不孕问题的女性与认为自己存在生育问题的女性在不孕与主观幸福感之间的关联是否存在差异。

参与者/材料、设置、方法:所有 283 名参与者在两次波次(相隔 3 年)中都接受了抑郁症状(使用流行病学研究中心抑郁量表测量)、自尊心(使用罗森伯格自尊量表的改良版测量)和生活满意度(使用生活满意度量表的改良版测量)的评估。对于所有三个变量,通过活产解决不孕问题的 47 名非自愿无子女女性的变化分数与 236 名仍无子女的女性的分数进行了比较。纳入了一些已知与不孕女性的主观幸福感相关的变量作为对照。

主要结果和机会的作用

没有观察到不孕解决与抑郁症状变化之间的关系(b=-0.04;P>0.05)。解决不孕问题的非自愿无子女女性自尊心(b=0.74;P<0.01)和生活满意度(b=1.06;P<0.01)有所提高。

局限性、谨慎的原因:女性仅在两个时间点进行了测量。两次波次之间只有 47 名女性分娩。虽然基于面板数据进行因果推断是常见做法,但这种推断应该谨慎进行。此外,NSFB 是在美国进行的,在美国医疗支出较高,大多数生育治疗费用都不在保险范围内。因此,这些发现可能无法推广到其他现代工业化社会。

研究结果的更广泛意义

了解解决不孕问题与主观幸福感的提高有关,这对不孕夫妇和不孕不育专业人士都很重要。

研究资金/利益冲突:本研究部分得到美国国立卫生研究院 NICHD 授予的 R01-HD044144 号和 NIGMS 授予的 P20-GM109097 号资助。作者没有利益冲突。

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