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接受辅助生殖技术治疗的患者的生活质量及其预测因素。

Quality of life and predictive factors in patients undergoing assisted reproduction techniques.

机构信息

Hospital Pharmacy Service, La Mancha-Centro Hospital, Ciudad Real, Spain.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2013 Apr;167(2):176-80. doi: 10.1016/j.ejogrb.2012.12.011. Epub 2013 Jan 21.

Abstract

OBJECTIVES

To evaluate the quality of life (QOL) of a cohort of women undergoing assisted reproduction techniques (ART), to compare two QOL questionnaires [Short Form 36 (SF36) and FertiQoL], and to identify the predictive factors related to QOL.

STUDY DESIGN

Women who received infertility medication from a hospital pharmacist during a one-year period were included in this study. Two standardized validated questionnaires - FertiQoL and SF36 - were used. Multivariate analyses were used to assess predictive factors for QOL.

RESULTS

Sixty-one women participated in this study. Median QOL scores ranged from 58 to 100. Comparisons between the two questionnaires revealed lower QOL scores when using FertiQoL. Most correlations between the questionnaires were positive, and significant for the majority of SF36 mental dimensions. The major predictors of QOL were: accompanied to the pharmacist's visit by partner, nationality, ART (in vitro fertilization or artificial insemination), employment status (employed or unemployed), tobacco consumption, age, number of cycles, infertility factor and treatment results (pregnancy, no pregnancy or treatment cancellation).

CONCLUSIONS

FertiQoL examines dimensions such as partner and social relationships. As such, it is recommended that FertiQoL should be used together with a short version of SF36 to investigate QOL among patients undergoing ART.

摘要

目的

评估接受辅助生殖技术(ART)的女性队列的生活质量(QOL),比较两种 QOL 问卷[短格式 36(SF36)和 FertiQoL],并确定与 QOL 相关的预测因素。

研究设计

本研究纳入了在一年内接受医院药剂师不孕药物治疗的女性。使用了两种标准化的验证问卷 - FertiQoL 和 SF36 - 。采用多变量分析评估 QOL 的预测因素。

结果

61 名女性参与了这项研究。中位 QOL 评分范围为 58 至 100。两个问卷之间的比较显示,使用 FertiQoL 时 QOL 评分较低。大多数问卷之间的相关性为正,并且对大多数 SF36 心理维度具有重要意义。QOL 的主要预测因素是:由伴侣陪同去药剂师就诊、国籍、ART(体外受精或人工授精)、就业状况(就业或失业)、吸烟状况、年龄、周期数、不孕因素和治疗结果(怀孕、未怀孕或治疗取消)。

结论

FertiQoL 检查了伴侣和社会关系等方面。因此,建议在调查接受 ART 的患者的 QOL 时,应将 FertiQoL 与 SF36 的简短版本一起使用。

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