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[节律性运动脊髓发生器活动的数学模型]

[A mathematical model of the activity of spinal generators of rhythmic movements].

作者信息

Degtiarenko A M

出版信息

Neirofiziologiia. 1988;20(5):586-97.

PMID:3211222
Abstract

Different organization schemes concerning locomotor and scratching rhythmicity generators are analyzed by means of the mathematical simulation model. A functional group of neurons (half-centre constructed on the stochastically organized neuronal network) is the basis for generator. Some organization schemes concerning locomotor and scratching rhythmicity generators are considered, such as: two half-centres with reciprocal inhibitory connections and tonic excitatory influences on these half-centres: two half-centres with inhibitory-excitatory connections and tonic excitatory influences on one half-centre; ring structures consisting of more than two functional groups of neurons with excitatory and inhibitory connections between them. In all the schemes considered generation of rhythmic activity is possible with time characteristics similar to those of the locomotor and scratching rhythmicity. It is shown that transition from locomotor to scratching rhythmicity can be realized through simply organized actions on generator neurons. Possible principles of construction of spinal generators for locomotor and scratching movements are discussed.

摘要

通过数学模拟模型分析了有关运动和抓挠节律发生器的不同组织方案。一组功能性神经元(基于随机组织的神经网络构建的半中枢)是发生器的基础。考虑了一些有关运动和抓挠节律发生器的组织方案,例如:具有相互抑制性连接且对这些半中枢有紧张性兴奋性影响的两个半中枢;具有抑制 - 兴奋性连接且对一个半中枢有紧张性兴奋性影响的两个半中枢;由两个以上功能性神经元组组成的环状结构,它们之间具有兴奋性和抑制性连接。在所有考虑的方案中,都有可能产生具有与运动和抓挠节律相似时间特征的节律性活动。结果表明,通过对发生器神经元进行简单组织的操作,可以实现从运动节律到抓挠节律的转变。讨论了用于运动和抓挠运动的脊髓发生器构建的可能原则。

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