Case report and review of the potential role of the Type A piriformis muscle in dynamic sciatic nerve entrapment variant of piriformis syndrome.

Piriformis syndrome (PS) is an underdiagnosed but common cause of chronic buttock pain and sciatica. Anatomical variants of the piriformis muscle and sciatic nerve have not been thought to be significant in the pathophysiology of PS however, recent description of the piriformis musculotendinous junction has identified a common variant that we believe frequently results in dynamic sciatic nerve entrapment at the infra-piriformis fossa. We performed ultrasound guided low-dose Botulinum Toxin-A (BTX-A) injection to the lower piriformis muscle belly in an elite Australian Rules football player with PS and Type A piriformis muscle to relieve symptomatic sciatic nerve compression. Positive response to targeted BTX-A piriformis muscle injections support the hypothesis that sciatic nerve compression by Type A piriformis muscles may contribute to the pathophysiology of neuropathic PS, along with other functional factors. Sciatic nerve compression due to Type A piriformis at the infra-piriformis fossa has not been described previously and is a potentially common cause of neuropathic PS, especially when combined with other functional factors such as piriformis muscle spasm/hypertrophy and sacroiliac joint counternutation.