Kostiukov A I
Neirofiziologiia. 1988;20(5):694-702.
Processes of length changes evoked by ramp-and-hold alterations in the external load were studied in ankle extensor of anesthetized cats under conditions of constant frequency of efferent stimulation. Basing on the experimental data a phenomenological theory of muscle dynamics was elaborated. It was shown that the system under study could be presented as a system with nonlinear statics and linear dynamics. The nonlinear statics was shown to be determined mainly by hysteretical effects of muscle contraction. A hypothesis was proposed to explain the hysteresis in active muscle on the basis of functioning of the troponin-tropomyosin regulatory complex. Dynamic element in the model was described by the first order linear differential equation corresponding to a three-component visco-elastic muscle model. The suggested phenomenological theory of muscle dynamics can be used to describe lengthening processes but satisfactory results were obtained only for rather slow load increments.
在传出刺激频率恒定的条件下，研究了麻醉猫的踝伸肌中由外部负荷的斜坡-保持变化引起的长度变化过程。基于实验数据，阐述了肌肉动力学的唯象理论。结果表明，所研究的系统可表示为具有非线性静力学和线性动力学的系统。非线性静力学主要由肌肉收缩的滞后效应决定。提出了一个假设，以基于肌钙蛋白-原肌球蛋白调节复合体的功能来解释活性肌肉中的滞后现象。模型中的动态元件由对应于三分量粘弹性肌肉模型的一阶线性微分方程描述。所提出的肌肉动力学唯象理论可用于描述伸长过程，但仅在相当缓慢的负荷增加时才获得满意的结果。
