Division of Pediatric Sleep Medicine, University of South Carolina, Prisma Health, Greenville, SC, USA.
J Sleep Res. 2020 Dec;29(6):e13027. doi: 10.1111/jsr.13027. Epub 2020 Feb 29.
Recurrent isolated sleep paralysis can be very disturbing and provoke anxiety. The majority of patients can be treated conservatively with cognitive and behavioural therapies. However, some patients may benefit from a pharmacologic intervention. With only scant available evidence, there are currently no standardized pharmacologic treatment recommendations for recurrent isolated sleep paralysis. We report the first two cases of escitalopram used to successfully treat recurrent isolated sleep paralysis. Escitalopram, the most selective of the selective serotonin reuptake inhibitors, generally improves subjective sleep quality, making it an appealing treatment option.
反复发作的孤立性睡眠瘫痪可能会非常困扰，并引发焦虑。大多数患者可以通过认知和行为疗法进行保守治疗。然而，一些患者可能受益于药物干预。由于可用的证据很少，目前对于反复发作的孤立性睡眠瘫痪没有标准化的药物治疗建议。我们报告了使用艾司西酞普兰成功治疗反复发作的孤立性睡眠瘫痪的前两例病例。艾司西酞普兰是选择性 5-羟色胺再摄取抑制剂中选择性最高的一种，通常可以改善主观睡眠质量，因此成为一种有吸引力的治疗选择。
