Kolek Antonín, Prasko Jan, Vanek Jakub, Kantor Krystof, Holubova Michaela, Slepecky Milos, Nesnidal Vlastimil, Latalova Klara, Ociskova Marie, Grambal Ales
Department of Psychiatry, Faculty of Medicine and Dentistry, University Palacky Olomouc, University Hospital, 77520 Olomouc, Czech Republic.
Department of Psychiatry, Hospital Liberec, Czech Republic.
Neuro Endocrinol Lett. 2019 Dec;40(5):233-246.
Little is known about the relation between severity of panic disorder, adverse events in childhood, dissociation, self-stigma and comorbid personality disorders. The aim of this study is to look for the intercorrelations between these factors.
The study explores the relation between clinical, demographic and social factors in panic disorder using cross sectional design. The inpatients with pharmacoresistant panic disorder with and without agoraphobia were included in the study. Participants were also assessed for comorbidity with other anxiety or personality disorder. The Clinical Global Impression (CGI), Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI-II), Dissociative Experiences Scale (DES), Internalized Stigma of Mental Illness (ISMI), Childhood Trauma Questionnaire-Short Form (CTQ-SF), Panic Disorder Severity Scale (PDSS) and demographic data were used as measurement tools.
A total of 142 pharmacoresistant patients with panic disorder with or without agoraphobia were admitted for 6-week cognitive behavioral therapy inpatient program in psychotherapeutic department between November 2015 and July 2019. One hundred and five inpatients (33 males and 72 females) with mean age 37.8 + 12.1 years were included in the study. Sixty-nine patients suffer from additional comorbid anxiety disorder and 43 had comorbid personality disorder.
关于惊恐障碍的严重程度、童年不良事件、分离、自我污名化与共病性人格障碍之间的关系，目前所知甚少。本研究旨在探寻这些因素之间的相互关系。
本研究采用横断面设计，探讨惊恐障碍的临床、人口统计学和社会因素之间的关系。纳入了患有和未患有广场恐惧症的药物抵抗性惊恐障碍住院患者。还评估了参与者是否合并其他焦虑或人格障碍。使用临床总体印象量表（CGI）、贝克焦虑量表（BAI）、贝克抑郁量表（BDI-II）、分离体验量表（DES）、精神疾病内化污名量表（ISMI）、儿童创伤问卷简表（CTQ-SF）、惊恐障碍严重程度量表（PDSS）和人口统计学数据作为测量工具。
2015年11月至2019年7月期间，共有142例患有或未患有广场恐惧症的药物抵抗性惊恐障碍患者被收治到心理治疗科接受为期6周的认知行为治疗住院项目。105例住院患者（33名男性和72名女性）被纳入研究，平均年龄为37.8 ± 12.1岁。69例患者患有额外的共病性焦虑障碍，43例患有共病性人格障碍。
