School of Biomedical Engineering, College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong, 518060, China.
Research Center for Bioengineering and Sensing Technology, University of Science & Technology Beijing, Beijing, 100083, China.
Talanta. 2020 May 15;212:120801. doi: 10.1016/j.talanta.2020.120801. Epub 2020 Jan 31.
Wearable sweat sensors demonstrate outstanding performance in non-invasive, real-time monitoring of vital biomarkers in sweat, which offer an opportunity for individuals to achieve dynamic monitoring their own physiology in molecular-level. As a key step in sweat analysis that impact the accuracy of results, frequently-used sweat sampling methods are introduced in this review, and the emphasis is sweat sampling in wearable sensors including absorbent materials, superhydrophobic/superhydrophilic surface, sweat guidance and epidermal microfluidic systems. In the end, we also propose the remaining challenges in the practical, large-scale application of wearable sweat sensors and provide personal prospects on the future development.
可穿戴汗液传感器在无创、实时监测汗液中的重要生物标志物方面表现出色，为人们实现分子水平上的动态监测自身生理机能提供了机会。作为影响结果准确性的汗液分析的关键步骤，本综述介绍了常用的汗液采样方法，并重点介绍了可穿戴传感器中的汗液采样方法，包括吸水性材料、超疏水/超亲水表面、汗液引导和表皮微流控系统。最后，我们还提出了可穿戴汗液传感器在实际大规模应用中存在的挑战，并对未来的发展提出了个人展望。
