Department of Interventional Radiology, Centre Léon Berard, 28 Prom. Léa Et Napoléon Bullukian, 69008 Lyon, France.
Department of Interventional Radiology, Centre Léon Berard, 28 Prom. Léa Et Napoléon Bullukian, 69008 Lyon, France.
J Vasc Interv Radiol. 2020 Apr;31(4):558-563.e3. doi: 10.1016/j.jvir.2019.10.024. Epub 2020 Feb 26.
To evaluate the efficacy and safety of cryoablation for venous malformations.
A total of 12 patients with symptomatic intramuscular venous malformations who underwent percutaneous cryoablation between February 2015 and December 2018 were retrospectively studied. The mean age was 42 y (range, 19-58 y). Pain was reported by 11 patients (92%) and swelling by 1 (8%). Pain was assessed with a visual analog scale (VAS) before and after cryoablation. Lesion size was followed with magnetic resonance (MR) imaging at baseline and at 3-mo follow-up. Median initial VAS score was 7 (range, 0-8), and median initial lesion size was 32.5 mm (range, 11-150 mm).
The median VAS score at 3 mo was 0 (range, 0-4), and the median lesion size at 3 mo was 0 mm (range, 0-142 mm). Eleven of 12 patients reported an improvement in their pain. MR imaging control showed a treatment scar with no residual lesion in 5 patients and decreased lesion size in 4. No major complications were reported. One minor hematoma and 1 small myositis were noted as defined by Society of Interventional Radiology criteria.
Percutaneous cryoablation is effective and safe for treatment of symptomatic intramuscular venous malformations, with improvement of symptoms.
评估冷冻消融治疗静脉畸形的疗效和安全性。
回顾性研究了 2015 年 2 月至 2018 年 12 月期间接受经皮冷冻消融治疗的 12 例有症状的肌内静脉畸形患者。平均年龄为 42 岁（范围，19-58 岁）。11 例（92%）患者报告有疼痛，1 例（8%）患者报告有肿胀。疼痛在冷冻消融前后采用视觉模拟评分（VAS）进行评估。基线和 3 个月随访时采用磁共振成像（MR）对病变大小进行随访。初始 VAS 评分中位数为 7（范围，0-8），初始病变大小中位数为 32.5mm（范围，11-150mm）。
3 个月时的 VAS 评分中位数为 0（范围，0-4），3 个月时的病变大小中位数为 0mm（范围，0-142mm）。12 例患者中有 11 例报告疼痛改善。MR 成像对照显示 5 例患者有治疗性瘢痕，无残留病变，4 例患者病变大小减小。未报告重大并发症。根据介入放射学会的标准，有 1 例小血肿和 1 例小肌炎被定义为轻微并发症。
经皮冷冻消融治疗有症状的肌内静脉畸形是有效且安全的，可以改善症状。
