Fitzsimons R, Lee J P, Elston J
Moorfields Eye Hospital, London.
Ophthalmology. 1988 Nov;95(11):1535-42. doi: 10.1016/s0161-6420(88)32976-3.
This study reports the results of treating unrecovered sixth nerve palsy in adults with a combination of botulinum toxin and surgery. Twenty-two adults, 11 with unilateral and 11 with bilateral unrecovered sixth nerve palsy, were treated with injections of botulinum toxin to the contracted medial rectus followed by transposition surgery to the vertical rectus muscles. This management technique produced a satisfactory reduction in esotropia, averaging 46 prism diopters (PD), comparable with that achieved by conventional surgery in other series. The advantages of this form of treatment are discussed.
本研究报告了肉毒杆菌毒素与手术联合治疗成人未恢复性第六神经麻痹的结果。22名成年人，其中11名单侧、11名双侧未恢复性第六神经麻痹患者，接受了向收缩的内直肌注射肉毒杆菌毒素，随后对垂直直肌进行转位手术。这种治疗技术使内斜视得到了令人满意的改善，平均减少46棱镜度（PD），与其他系列常规手术所取得的效果相当。本文讨论了这种治疗方式的优点。
