Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, Queensland, Australia.
Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Clin Anat. 2020 Sep;33(6):887-898. doi: 10.1002/ca.23585. Epub 2020 Mar 12.
Intramedullary nailing is the surgical method of choice for the treatment of proximal femur or femoral shaft fractures. Implant manufacturers aim to design implants fitting for the broadest possible population segment. As complete morphological data sets of long bones are not widely available, anatomical collections of historical dry bone specimens may represent abundant additional sources of morphological three-dimensional (3D) data for implant design, provided they are consistent with present populations. This study aims to investigate secular trends and age-related changes of femoral morphology of the Caucasian population over the past 800 years.
Computer graphical measurements of 3D-datasets of right and left femora derived from computed tomography (CT) scans, representative of the present Caucasian population, were compared to computer graphical measurements of 3D-datasets of right and left femora derived from CT scans of specimens from a historical medieval European bone collection.
Clinically relevant parameters of historical medieval European femora were found mostly consistent with correlative data of the present Caucasian population. Additionally, for some of the evaluated parameters, particularly anteversion, morphological differences significantly correlated to individual age and sex could be identified, whereas other parameters such as caput-collum-diaphyseal angle or radius of anterior femoral bowing were not correlated to individual age or sex.
The findings suggest that more recent historical specimen collections may be a convenient and easily accessible source of new 3D morphological data, as well as to complement existing data, to be used by researchers and manufacturers for the development of intramedullary femoral nails.
髓内钉是治疗股骨近端或股骨干骨折的首选手术方法。植入物制造商的目标是设计适合尽可能广泛人群的植入物。由于完整的长骨形态数据集并不广泛，历史干骨标本的解剖收藏可能代表了用于植入物设计的大量额外形态三维（3D）数据来源，只要它们与当前人群一致。本研究旨在调查过去 800 年来白种人群股骨形态的 secular 趋势和与年龄相关的变化。
对来自 CT 扫描的右股骨和左股骨的 3D 数据集进行计算机图形测量，这些数据集代表了当前的白种人群，并将其与来自历史上的欧洲中世纪骨骼收藏的 CT 扫描的右股骨和左股骨的 3D 数据集进行计算机图形测量进行比较。
历史上的欧洲中世纪股骨的临床相关参数大多与当前白种人群的相关数据一致。此外，对于一些评估参数，特别是前倾角，可识别与个体年龄和性别相关的形态差异，而其他参数，如股骨头颈干角或前股骨弯曲半径，则与个体年龄或性别无关。
研究结果表明，更近的历史标本收藏可能是一种方便且易于获取的新 3D 形态数据来源，可以补充现有数据，供研究人员和制造商用于开发髓内股骨钉。
