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[针灸促进骨折愈合的机制研究进展]

[Research progress on mechanism of acupuncture and moxibustion promoting fracture healing].

作者信息

Chen Ji-Wen, Wang Hua-Jun, Zheng Xiao-Fei

机构信息

Bone Joint and Sport Medical Center, the First Clinical College of Jinan University, the First Affiliated Hospital of Jinan University, Guangzhou 510630, Guangdong, China.

出版信息

Zhongguo Gu Shang. 2020 Jan 25;33(1):93-6. doi: 10.3969/j.issn.1003-0034.2020.01.018.

Abstract

Acupuncture has a significant effect on promoting fracture healing. It can dredge meridians and collaterals, regulate qi and blood, eliminate swelling and remove stasis. However, its mechanism is still not fully elucidated. With the development of research, it has been found in recent years that the mechanism of acupuncture and moxibustion promoting fracture healing involves regulating the expression level of cell growth factor, activating Wnt/β-Catenin and other signal pathways, improving local blood circulation, affecting the content of mineral elements in bone, regulating the endocrine system, promoting the differentiation and proliferation of bone cells, promoting the proliferation and activation of osteoblasts and influencing the apoptosis of bone cells And so on. The mechanism of acupuncture and moxibustion promoting fracture healing is very complex, which is still at the level of animal experiments and cells.

摘要

针灸对促进骨折愈合有显著作用。它能疏通经络、调节气血、消肿化瘀。然而,其机制仍未完全阐明。随着研究的发展,近年来发现针灸促进骨折愈合的机制涉及调节细胞生长因子的表达水平、激活Wnt/β-连环蛋白等信号通路、改善局部血液循环、影响骨中矿物质元素含量、调节内分泌系统、促进骨细胞分化与增殖、促进成骨细胞增殖与活化以及影响骨细胞凋亡等。针灸促进骨折愈合的机制非常复杂,目前仍处于动物实验和细胞水平。

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