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2
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DNA Recognition by Hybrid Oligoether-Oligodeoxynucleotide Macrocycles.通过混合寡醚 - 寡脱氧核苷酸大环识别DNA
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本文引用的文献

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Reversible bending and helix geometry in a B-DNA dodecamer: CGCGAATTBrCGCG.B-DNA十二聚体中的可逆弯曲和螺旋几何结构：CGCGAATTBrCGCG
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Poly(pyrimidine) . poly(purine) synthetic DNAs containing 5-methylcytosine form stable triplexes at neutral pH.含有5-甲基胞嘧啶的聚（嘧啶）·聚（嘌呤）合成DNA在中性pH下形成稳定的三链体。
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Association of an S1 nuclease-sensitive structure with short direct repeats 5' of Drosophila heat shock genes.果蝇热休克基因5'端短正向重复序列与S1核酸酶敏感结构的关联。
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An altered DNA conformation detected by S1 nuclease occurs at specific regions in active chick globin chromatin.通过S1核酸酶检测到的DNA构象改变发生在活跃的鸡珠蛋白染色质的特定区域。
Cell. 1982 Jun;29(2):609-22. doi: 10.1016/0092-8674(82)90177-5.
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Homocopolymer sequences in the spacer of a sea urchin histone gene repeat are sensitive to S1 nuclease.海胆组蛋白基因重复序列间隔区中的同聚物序列对S1核酸酶敏感。
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Specificity of the three-stranded complex formation between double-stranded DNA and single-stranded RNA containing repeating nucleotide sequences.双链DNA与含有重复核苷酸序列的单链RNA之间三链复合物形成的特异性。
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The interpretation of protein structures: estimation of static accessibility.蛋白质结构的解读：静态可及性的评估
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Physical and chemical characterization of two- and three-stranded adenine-thymine and adenine-uracil homopolymer complexes.双链和三链腺嘌呤-胸腺嘧啶以及腺嘌呤-尿嘧啶同聚物复合物的物理和化学特性
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Structures for the polynucleotide complexes poly(dA) with poly (dT) and poly(dT) with poly(dA) with poly (dT).聚（dA）与聚（dT）以及聚（dT）与聚（dA）和聚（dT）形成的多核苷酸复合物的结构
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10
Molecular dynamics simulations of d(C-G-C-G-A) X d(T-C-G-C-G) with and without "hydrated" counterions.含和不含“水合”抗衡离子的d(C-G-C-G-A)×d(T-C-G-C-G)的分子动力学模拟
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寡嘌呤-寡嘧啶三链体中的DNA茎环结构

DNA stem-loop structures in oligopurine-oligopyrimidine triplexes.

作者信息

Harvey S C, Luo J, Lavery R

机构信息

Department of Biochemistry, University of Alabama, Birmingham 35294.

出版信息

Nucleic Acids Res. 1988 Dec 23;16(24):11795-809. doi: 10.1093/nar/16.24.11795.

DOI:10.1093/nar/16.24.11795
PMID:3211749
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC339111/
Abstract

Closed circular DNA containing polypurine-polypyrimidine sequences can adopt a triple helical stem-loop structure under supercoiling pressure. We describe an automated procedure for building model loops and its application to the investigation of the polypyrimidine loop at the end of such a triple helical stem. All possible combinations of 3'-stacked and 5'-stacked structures have been examined for loops containing three, four, five, and six nucleotides. The lowest energy conformation is a four-membered loop with all bases stacked on the strand at the 3' end of the loop. The model predicts that sequences (GA)n, (GGGA)n and (GAAA)n should form the stem-loop structure more easily than (GGA)n and (GAA)n. It is also predicted that when a polypurine-polypyrimidine sequence converts from a double stranded structure to a triple stranded stem-loop, the most favorable conditions are those where an even number of basepairs makes the transition. Experimental tests of these predictions are also described.

摘要

含有聚嘌呤-聚嘧啶序列的闭环DNA在超螺旋压力下可形成三螺旋茎环结构。我们描述了一种构建模型环的自动化程序及其在研究此类三螺旋茎末端的聚嘧啶环中的应用。对于包含三个、四个、五个和六个核苷酸的环，已研究了3'-堆积和5'-堆积结构的所有可能组合。能量最低的构象是一个四元环，所有碱基都堆积在环3'端的链上。该模型预测，序列(GA)n、(GGGA)n和(GAAA)n比(GGA)n和(GAA)n更容易形成茎环结构。还预测，当聚嘌呤-聚嘧啶序列从双链结构转变为三链茎环时，最有利的条件是偶数个碱基对发生转变的情况。文中还描述了对这些预测的实验测试。