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印度中部一所三级机构对年轻消化性溃疡穿孔患者的前瞻性临床内镜随访研究。

A Prospective Clinicoendoscopic Follow-up Study in Young Patients with Peptic Ulcer Perforation at a Tertiary Institute in Central India.

作者信息

Jahagirdaar Deepa, Bomanwar Nitin, Joshi Sneha

机构信息

Department of General Surgery, Government Medical College and Hospital, Nagpur, Maharashtra, India.

Department of Surgical Oncology, Kingsway Hospitals, Nagpur, Maharashtra, India.

出版信息

Euroasian J Hepatogastroenterol. 2019 Jul-Dec;9(2):91-95. doi: 10.5005/jp-journals-10018-1306.

DOI:10.5005/jp-journals-10018-1306
PMID:32117697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7047314/
Abstract

BACKGROUND

Perforation peritonitis is one of the commonest encountered emergencies in the surgery casualty. This study was conducted with the aim of identifying risk factors in peptic ulcer disease (PUD) in young patients.

MATERIALS AND METHODS

Seventy patients were evaluated in this study and were followed up with clinical examination and endoscopy at 8 weeks and 6 months.

RESULTS

Out of the total 70 patients, there was a mortality of 5 patients and 7 patients were lost to follow-up. Out of the remaining 57 patients, 56 were men and 1 was a woman. Maximum patients were from the age group of 35-40 years. The patients were categorized on the basis of their clinical symptoms and endoscopy results at the follow-up of 6 months in 4 categories-21 patients having an active ulcer and symptomatic, 15 patients having active ulcer but no symptoms, 16 patients who were asymptomatic and without an active ulcer and 5 patients nonulcer dyspepsia.

CONCLUSION

Postoperative treatment with H blockers or proton pump inhibiters along with anti- regimen should be prescribed for all patients with peptic ulcer perforation. Routine endoscopic examination of such patients should also form a part of the follow-up to look for ulcer healing postoperatively.

HOW TO CITE THIS ARTICLE

Jahagirdaar D, Bomanwar N, Joshi S. A Prospective Clinicoendoscopic Follow-up Study in Young Patients with Peptic Ulcer Perforation at a Tertiary Institute in Central India. Euroasian J Hepato-Gastroenterol 2019;9(2):91-95.

摘要

背景

穿孔性腹膜炎是外科急诊中最常见的病症之一。本研究旨在确定年轻患者消化性溃疡病(PUD)的风险因素。

材料与方法

本研究评估了70例患者,并在8周和6个月时通过临床检查和内镜检查进行随访。

结果

在总共70例患者中,有5例死亡,7例失访。在其余57例患者中,56例为男性,1例为女性。最大年龄组为35 - 40岁。根据6个月随访时的临床症状和内镜检查结果,将患者分为4类:21例有活动性溃疡且有症状,15例有活动性溃疡但无症状,16例无症状且无活动性溃疡,5例为非溃疡性消化不良。

结论

对于所有消化性溃疡穿孔患者,均应开具H受体阻滞剂或质子泵抑制剂联合抗感染治疗的术后治疗方案。对此类患者进行常规内镜检查也应作为随访的一部分,以观察术后溃疡愈合情况。

如何引用本文

贾哈吉尔达尔D,博曼瓦尔N,乔希S。印度中部一所三级医疗机构对年轻消化性溃疡穿孔患者的前瞻性临床内镜随访研究。《欧亚肝脏胃肠病学杂志》2019年;9(2):91 - 95。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7ac/7047314/118430e2a2fd/ejohg-9-91-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7ac/7047314/463a97f2b399/ejohg-9-91-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7ac/7047314/118430e2a2fd/ejohg-9-91-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7ac/7047314/463a97f2b399/ejohg-9-91-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7ac/7047314/118430e2a2fd/ejohg-9-91-g002.jpg

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A Five-Year Review of Perforated Peptic Ulcer Disease in Irrua, Nigeria.尼日利亚伊鲁阿地区消化性溃疡穿孔疾病的五年回顾
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Therapeutic management of perforated gastro-duodenal ulcer: literature review.穿孔性胃十二指肠溃疡的治疗管理:文献综述。
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Progress after Perforated Peptic Ulcer.消化性溃疡穿孔后的进展
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