抗中性粒细胞胞浆抗体相关性血管炎

ANCA-Associated Vasculitis

作者信息

Qasim Abdallah, Patel Jayesh B.

机构信息

Creighton University

University of Iowa Hospitals and Clinics

PMID:32119259

Abstract

Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitides are a heterogeneous group of rare autoimmune conditions that cause inflammation of blood vessels with various manifestations. This group includes 3 main diseases—granulomatosis with polyangiitis (GPA), formerly known as Wegener granulomatosis; eosinophilic granulomatosis with polyangiitis (EGPA), previously known as Churg-Strauss syndrome; and microscopic polyangiitis (MPA). Other ANCA-associated diseases include drug-induced vasculitis and renal-limited vasculitis. Please see StatPearls' companion resources, "Granulomatosis with Polyangiitis," "Eosinophilic Granulomatosis with Polyangiitis," "Microscopic Polyangiitis," and "Rapidly Progressive Glomerulonephritis," for further information.

摘要

抗中性粒细胞胞浆抗体（ANCA）相关血管炎是一组罕见的异质性自身免疫性疾病，可导致血管炎症并伴有各种表现。这组疾病包括3种主要疾病——肉芽肿性多血管炎（GPA），以前称为韦格纳肉芽肿；嗜酸性肉芽肿性多血管炎（EGPA），以前称为变应性肉芽肿性血管炎；以及显微镜下多血管炎（MPA）。其他ANCA相关疾病包括药物性血管炎和局限于肾脏的血管炎。有关更多信息，请参阅StatPearls的配套资源“肉芽肿性多血管炎”、“嗜酸性肉芽肿性多血管炎”、“显微镜下多血管炎”和“急进性肾小球肾炎”。