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神经解剖学,额叶皮质

Neuroanatomy, Frontal Cortex

作者信息

El-Baba Rami M., Schury Mark P.

机构信息

MSU-College of Osteopathic Medicine

McLaren Oakland

Abstract

The cerebral cortex is the outermost portion of the brain, containing billions of tightly packed neuronal cell bodies that form what is known as the gray matter of the brain. The white matter of the brain and spinal cord forms as heavily myelinated axonal projections of these neuronal cell bodies. The cerebral cortex has four major divisions known as lobes: the frontal, temporal, parietal, and occipital lobes. Each of these lobes has developed evolutionarily distinct and important functions. The surface of the cortex has a characteristic 'bumps and grooves' appearance, with the bumps referring to foldings of the cortex known as gyri, and the grooves referring to the sulci, which separate them.  These foldings allow for the large cortical volume to fit inside the limited space of the cranial vault. The sulci are anatomical divides that separate the lobes from one another.  The lateral cerebral fissure, also known as the Sylvian fissure, separates the temporal lobe from the parietal and frontal lobe.  There is also the central sulcus, which is the divide between the frontal and parietal lobes, the parieto-occipital sulcus divides the parietal and occipital lobes, and the calcarine fissure which separates the cuneus from the lingual gyrus.   The focus of this article is on the cortex of the frontal lobe, the largest of the four, and in many ways the lobe which participates most in making us human. It is located at the most rostral (anterior) region of each cerebral hemisphere, separated from the parietal lobe by the central sulci and the temporal lobe by the lateral cerebral (Sylvian) fissure.  Particular regions of the frontal cortex are responsible for numerous capabilities, most notably the performance of motor tasks, judgment, abstract thinking, creativity, and maintaining social appropriateness.

摘要

大脑皮层是大脑的最外层,包含数十亿紧密排列的神经元细胞体,这些细胞体构成了所谓的大脑灰质。大脑和脊髓的白质是这些神经元细胞体的大量有髓轴突投射形成的。大脑皮层有四个主要分区,称为脑叶:额叶、颞叶、顶叶和枕叶。这些脑叶在进化过程中各自发展出了独特且重要的功能。皮层表面呈现出特有的“凹凸不平”外观,凸起部分指的是皮层的褶皱,称为脑回,而凹槽指的是将它们分隔开的脑沟。这些褶皱使得巨大的皮层体积能够容纳在颅腔内有限的空间内。脑沟是将各个脑叶彼此分隔开的解剖学界限。大脑外侧裂,也称为西尔维厄斯裂,将颞叶与顶叶和额叶分隔开。还有中央沟,它是额叶和顶叶之间的分界线,顶枕沟将顶叶和枕叶分开,距状沟将楔叶与舌回分开。本文的重点是额叶皮层,它是四个脑叶中最大的,并且在许多方面是最能体现人类特质的脑叶。它位于每个大脑半球的最前端(前部)区域,通过中央沟与顶叶分开,通过大脑外侧(西尔维厄斯)裂与颞叶分开。额叶皮层的特定区域负责多种功能,最显著的是执行运动任务、判断、抽象思维、创造力以及保持社交得体性。

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