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权衡未来可能需要进行失禁手术与未来可能需要进行尿道吊带修复手术的可能性:接受盆腔器官脱垂手术的有控尿能力女性的权衡分析。

Balancing the possibility of needing a future incontinence procedure versus a future urethral sling revision surgery: a tradeoff analysis for continent women undergoing pelvic organ prolapse surgery.

机构信息

Department of Urology, Stanford University School of Medicine, Stanford, CA, USA.

Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA, USA.

出版信息

Int Urogynecol J. 2020 Jun;31(6):1141-1150. doi: 10.1007/s00192-020-04226-3. Epub 2020 Mar 3.

Abstract

INTRODUCTION AND HYPOTHESIS

Although urinary incontinence surgery has potential benefits such as preventing de novo stress urinary incontinence in women undergoing pelvic organ prolapse (POP) surgery, it comes with the potential cost of overtreatment and complications. We compared future surgery rates in a population cohort of women undergoing vaginal pelvic organ prolapse surgery.

METHODS

All women undergoing POP repair in California from 2005 to 2011 were identified from the Office of Statewide Health Planning and Development databases. Rates of repeat surgery in those with and without concomitant urethral sling procedures were compared. To control for confounding effects, multivariate mixed effects logistic regression models were constructed to compare each woman's individualized risk of undergoing either sling revision surgery or future incontinence surgery.

RESULTS

In the cohort, 38,456 underwent a sling procedure at the time of POP repair and 42,858 did not. The future surgery rate was higher for sling-related complications in the POP + sling cohort compared with future incontinence surgery in the POP alone cohort (3.5% versus 3.0% respectively, p < 0.001). The difference persisted in multivariate modeling, where most women (60%) are at a higher risk of requiring sling revision surgery compared with needing a future primary incontinence procedure (40%).

CONCLUSIONS

Women who undergo vaginal prolapse repair without an incontinence procedure are at a low risk of future incontinence surgery. Women without urinary incontinence who are considering vaginal POP surgery should be informed of the risks and benefits of including a sling procedure.

摘要

引言与假设

尽管尿失禁手术具有预防女性盆腔器官脱垂(POP)手术中新发压力性尿失禁的潜在益处,但也存在过度治疗和并发症的潜在风险。我们比较了接受阴道盆腔器官脱垂手术的人群队列中未来手术的发生率。

方法

从加利福尼亚州全州卫生规划和发展办公室数据库中确定了 2005 年至 2011 年间接受 POP 修复的所有女性。比较了伴有和不伴有尿道吊带手术的女性再次手术的发生率。为了控制混杂因素的影响,构建了多变量混合效应逻辑回归模型,以比较每位女性接受吊带修复手术或未来尿失禁手术的个体化风险。

结果

在队列中,38456 名女性在接受 POP 修复时接受了吊带手术,42858 名女性未接受。在 POP + 吊带队列中,吊带相关并发症的未来手术率高于单独 POP 队列中未来尿失禁手术率(分别为 3.5%和 3.0%,p<0.001)。在多变量建模中,这种差异仍然存在,大多数女性(60%)需要吊带修复手术的风险高于需要未来原发性尿失禁手术的风险(40%)。

结论

未接受尿失禁手术的女性在接受阴道脱垂修复后发生未来尿失禁手术的风险较低。不伴有尿失禁的女性如果考虑接受阴道 POP 手术,应告知其包括吊带手术的风险和益处。

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