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阴道分娩后急性致死性A组链球菌原发性腹膜炎

Acute fatal group A Streptococcal primary peritonitis following vaginal delivery.

作者信息

Aziz Daghmouri Mohamed, Affes Fatma Zahra, Jebri Alia, Boussassi Raja, Hamouda Sonia Ben, Bouguerra Badreddine, Houissa Mohamed

机构信息

Department of Anesthesia, Charles Nicolle Hospital, Tunis, Tunisia.

Department of Gynecology, Charles Nicolle Hospital, Tunis, Tunisia.

出版信息

IDCases. 2020 Feb 20;19:e00727. doi: 10.1016/j.idcr.2020.e00727. eCollection 2020.

Abstract

Acute primary peritonitis due to group A streptococci (GAS) is a rare but life-threatening disease most often seen in case of liver cirrhosis or nephrotic syndrome. The specific mechanism of this infection remains unknown and according to the literature hematogenous, lymphatic, retrograde inoculation from the genitourinary tract and translocation of intestinal tract flora have all been proposed. We report a case of a 37-year-old previously healthy patient who presented to the emergency, four days after vaginal delivery, with abdominal pain and septic shock. Acute peritonitis was diagnosed and peritoneal and blood culture revealed group A streptococci. Unfortunately, the patient died within 12 h despite adequate resuscitation and antimicrobials. The present case report highlights the importance of an early diagnosis with an adequate therapy in case of GAS peritonitis after vaginal delivery.

摘要

A 组链球菌(GAS)引起的急性原发性腹膜炎是一种罕见但危及生命的疾病,最常见于肝硬化或肾病综合征患者。这种感染的具体机制尚不清楚,根据文献报道,血行性、淋巴性、来自泌尿生殖道的逆行接种以及肠道菌群易位都曾被提出。我们报告一例 37 岁既往健康的患者,在阴道分娩后四天因腹痛和感染性休克就诊于急诊科。诊断为急性腹膜炎,腹腔和血培养显示为 A 组链球菌。不幸的是,尽管进行了充分的复苏和抗菌治疗,患者仍在 12 小时内死亡。本病例报告强调了阴道分娩后发生 GAS 腹膜炎时早期诊断并给予适当治疗的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dd/7042412/9e94548162d4/gr1.jpg

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