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孤立性胃肠道血管炎而无相关系统性疾病的肾移植受者,用利妥昔单抗治疗获得成功。

isolated gastrointestinal tract vasculitis without associated systemic disease in renal transplant recipients successfully treated with rituximab.

机构信息

Department of Nephrology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey.

Department of Gastroenterology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey.

出版信息

Saudi J Kidney Dis Transpl. 2020 Jan-Feb;31(1):281-284. doi: 10.4103/1319-2442.279954.

Abstract

Systemic vasculitic diseases can show recurrence after kidney transplantation, but de novo systemic vasculitis is rarely seen after kidney transplantation, and in literature, there are only a few cases. In general population, the incidence of isolated organ vasculitis is unknown, and according to the best of our knowledge, there is no information about de novo isolated organ vasculitis after renal transplantation. We report, most probably, the first case of a 40-year-old woman who was restarted on dialysis treatment after renal transplantation and developed isolated gastrointestinal vasculitis and intestinal hemorrhage under immunosuppressive treatment. She was treated successfully with rituximab.

摘要

系统性血管炎疾病在肾移植后可能会复发,但肾移植后新发系统性血管炎很少见,文献中仅有少数病例报道。在一般人群中,孤立性器官血管炎的发病率尚不清楚,据我们所知,尚无肾移植后新发孤立性器官血管炎的相关信息。我们报告了首例可能的病例,一名 40 岁女性,在肾移植后重新开始透析治疗,并在免疫抑制治疗下发生孤立性胃肠道血管炎和肠出血,最终成功接受利妥昔单抗治疗。

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