Instituto de Psiquiatria (IPUB), Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.
Danish Dementia Research Centre, University of Copenhagen, Copenhagen, Denmark.
Braz J Psychiatry. 2020;42(3):286-294. doi: 10.1590/1516-4446-2019-0539. Epub 2020 Feb 21.
To translate, establish the diagnostic accuracy, and standardize the Brazilian Portuguese version of the European Cross-Cultural Neuropsychological Test Battery (CNTB) considering schooling level.
We first completed an English-Brazilian Portuguese translation and back-translation of the CNTB. A total of 135 subjects aged over 60 years - 65 cognitively healthy (mean 72.83, SD = 7.71; mean education 9.42, SD = 7.69; illiterate = 25.8%) and 70 with Alzheimer's disease (AD) (mean 78.87, SD = 7.09; mean education 7.62, SD = 5.13; illiterate = 10%) - completed an interview and were screened for depression. The receiver operating characteristic (ROC) analysis was used to verify the accuracy of each CNTB test to separate AD from healthy controls in participants with low levels of education (≤ 4 years of schooling) and high levels of education (≥ 8 years of schooling). The optimal cutoff score was determined for each test.
The Recall of Pictures Test (RPT)-delayed recall and the Enhanced Cued Recall (ECR) had the highest power to separate AD from controls. The tests with the least impact from schooling were the Rowland Universal Dementia Assessment Scale (RUDAS), supermarket fluency, RPT naming, delayed recall and recognition, and ECR.
The Brazilian Portuguese version of the CNTB was well comprehended by the participants. The cognitive tests that best discriminated patients with AD from controls in lower and higher schooling participants were RPT delayed recall and ECR, both of which evaluate memory.
翻译、建立诊断准确性，并使欧洲跨文化神经心理测试电池（CNTB）的巴西葡萄牙语版本标准化，同时考虑到教育水平。
我们首先完成了 CNTB 的英语-巴西葡萄牙语翻译和回译。共有 135 名年龄在 60 岁以上的受试者 - 65 名认知健康（平均年龄 72.83，标准差= 7.71；平均受教育年限 9.42，标准差= 7.69；文盲= 25.8%）和 70 名阿尔茨海默病（AD）患者（平均年龄 78.87，标准差= 7.09；平均受教育年限 7.62，标准差= 5.13；文盲= 10%） - 完成了一次访谈，并接受了抑郁筛查。接收者操作特征（ROC）分析用于验证每个 CNTB 测试在受教育程度较低（≤4 年）和较高（≥8 年）的参与者中区分 AD 与健康对照组的准确性。确定了每个测试的最佳截断分数。
图片回忆测试（RPT）-延迟回忆和增强线索回忆（ECR）具有最高的能力将 AD 与对照组分开。受教育程度影响最小的测试是罗朗通用痴呆评估量表（RUDAS）、超市流畅度、RPT 命名、延迟回忆和识别以及 ECR。
参与者很好地理解了巴西葡萄牙语版的 CNTB。在受教育程度较低和较高的参与者中，能够最好地区分 AD 患者与对照组的认知测试是 RPT 延迟回忆和 ECR，两者都评估记忆。
