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来自三种刺桐属植物(刺桐、鸡冠刺桐和乔木刺桐)的人工合成刺桐生物碱

Artificial Erythrina Alkaloids from Three Erythrina Plants, E. variegata, E. crista-galli and E. arborescens.

作者信息

Zhang Bing-Jie, Wu Jing, Bao Mei-Fen, Wang Fang, Cai Xiang-Hai

机构信息

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China.

University of Chinese Academy of Sciences, Beijing, 100049, China.

出版信息

Nat Prod Bioprospect. 2020 Apr;10(2):57-66. doi: 10.1007/s13659-020-00235-3. Epub 2020 Mar 4.

Abstract

Fourteen unprecedented artificial Erythrina alkaloids were isolated from the Erythrina variegata, E. crista-galli and E. arborescens (Fabaceae). The structures of these alkaloids were determined by spectroscopic analyses. Their possible formations were proposed. All isolated compounds showed no cytotoxicity and hypoglycemic activity at cell screening bioassay.

摘要

从刺桐、鸡冠刺桐和乔木刺桐(豆科)中分离出了14种前所未有的人工刺桐生物碱。通过光谱分析确定了这些生物碱的结构,并提出了它们可能的形成方式。在细胞筛选生物测定中,所有分离出的化合物均未显示出细胞毒性和降血糖活性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f9e/7176790/59c0e1b66794/13659_2020_235_Fig1_HTML.jpg

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