UCLA-Kern Medical, Bakersfield, CA, USA.
J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620910636. doi: 10.1177/2324709620910636.
Coccidioidomycosis is an infection caused by inhalation of arthroconidia produced by dimorphic fungi in the genus . Forty percent of patients will develop an influenza-like illness with symptoms suggestive of a mild and self-limited respiratory infection; however, 5% of these individuals will develop extrapulmonary disseminated disease. An immunocompromised patient presented with right upper quadrant pain, ultrasound with pericholecystic fluid, in which a percutaneous cholecystostomy contained biliary fluid that grew the fungus . Patient was initiated on intravenous amphotericin therapy and was followed closely with postoperative bile drainage with eventual laparoscopic cholecystectomy. We present a very rare case of disseminated coccidioidomycosis to the gallbladder.
球孢子菌病是一种由双相真菌属中的节孢子引起的感染。40%的患者会出现类似流感的疾病,症状提示为轻度和自限性呼吸道感染;然而,其中 5%的患者会出现肺部外播散性疾病。一位免疫功能低下的患者出现右上腹疼痛,超声显示胆囊周围有液体,经皮胆囊造口术引流的胆汁中培养出真菌。患者开始接受静脉注射两性霉素治疗,并密切随访术后胆汁引流,最终行腹腔镜胆囊切除术。我们报告了一例非常罕见的播散性球孢子菌病累及胆囊的病例。