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质子束放射治疗在头皮血管肉瘤治疗中是否值得?

Is Proton Beam Radiotherapy Worthwhile in the Management of Angiosarcoma of the Scalp?

机构信息

National Center of Oncological Hadrontherapy (Fondazione CNAO), Pavia, Italy.

National Center of Oncological Hadrontherapy (Fondazione CNAO), Pavia, Italy

出版信息

Anticancer Res. 2020 Mar;40(3):1645-1649. doi: 10.21873/anticanres.14114.

Abstract

In inoperable patients, the management of angiosarcoma of the scalp is challenging. Due to intrinsic, dosimetric and radiobiological properties, proton beam radiotherapy may be an effective and safe option to offer to these difficult-to-cure patients. Here, we report a case of angiosarcoma of the scalp treated successfully with proton beam radiotherapy. Angiosarcoma is a rare malignancy concerning around 2% of soft-tissue sarcomas and 5% of cutaneous soft-tissue sarcomas. Cutaneous angiosarcomas can occur in any part of the body, but the head and neck region is a common primary site and the scalp is a frequent site in elderly patients.

摘要

对于无法手术的患者,头皮血管肉瘤的治疗具有挑战性。由于内在的、剂量学和放射生物学特性,质子束放射治疗可能是为这些难以治愈的患者提供的一种有效且安全的选择。在这里,我们报告了一例成功接受质子束放射治疗的头皮血管肉瘤病例。血管肉瘤是一种罕见的恶性肿瘤,约占软组织肉瘤的 2%和皮肤软组织肉瘤的 5%。皮肤血管肉瘤可发生于身体的任何部位,但头颈部是常见的原发部位,头皮是老年患者的常见部位。

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