Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.
Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota.
Cancer Epidemiol Biomarkers Prev. 2020 Apr;29(4):744-751. doi: 10.1158/1055-9965.EPI-19-0858. Epub 2020 Mar 4.
We field tested new-to-market portable, digital applications to assess hearing, pulmonary, and cognitive function to determine the feasibility of implementing these applications across a range of age groups in the pilot phase of the 10,000 Families Study (10KFS), a new Minnesota family-based prospective cohort study.
We followed manufacturer recommended protocols for audiometry (SHOEBOX Inc), spirometry (NuvoAir), and the digital clock drawing test (dCDT; Digital Cognition Technologies Inc).
These digital devices were low cost and readily implemented in a 2.5-hour health fair visit with minimal training (2-3 hours) of study staff. To date, we have performed these measurements on 197 eligible 10KFS participants during an in-person clinic visit. A total of 37 children (age 4-17 years), 107 adults (18-64 years), and 53 seniors (≥65 years) were eligible to undergo hearing and pulmonary assessments. Children were less likely to successfully complete the hearing test (76%) compared with adults (86%) and seniors (89%). However, successful completion of the pulmonary assessment was high across all groups: 100% of children and seniors and 98% of adults. The dCDT was performed among those over the age of 40, and completion rates were 92% for those aged 41-64 and 94% for those ≥65 years.
Our field testing indicates these digital applications are easy and cost-effective to implement in epidemiologic studies.
Digital applications provide exciting opportunities to collect data in population studies. Issues related to data privacy, data access, and reproducibility of measurements need to be addressed before deploying digital applications in epidemiologic studies.
我们对新推出的便携式数字应用程序进行了实地测试,以评估听力、肺部和认知功能,以确定在 10000 个家庭研究(10KFS)的试点阶段,将这些应用程序在一系列年龄组中实施的可行性,10000 个家庭研究是一项新的明尼苏达州基于家庭的前瞻性队列研究。
我们遵循制造商推荐的听力测试(SHOEBOX Inc)、肺活量测试(NuvoAir)和数字时钟绘制测试(dCDT;Digital Cognition Technologies Inc)的方案。
这些数字设备成本低廉,只需经过 2-3 小时的研究人员培训,即可在 2.5 小时的健康博览会上轻松实施。迄今为止,我们已经在面对面的诊所访问中对 197 名符合条件的 10KFS 参与者进行了这些测量。共有 37 名儿童(4-17 岁)、107 名成年人(18-64 岁)和 53 名老年人(≥65 岁)有资格进行听力和肺部评估。与成年人(86%)和老年人(89%)相比,儿童成功完成听力测试的可能性较低(76%)。然而,所有组的肺功能评估完成率都很高:儿童和老年人为 100%,成年人则为 98%。dCDT 是在 40 岁以上的人群中进行的,年龄在 41-64 岁的人群完成率为 92%,年龄在 65 岁以上的人群完成率为 94%。
我们的实地测试表明,这些数字应用程序易于实施且具有成本效益。
数字应用程序为在人群研究中收集数据提供了令人兴奋的机会。在将数字应用程序部署到流行病学研究中之前,需要解决与数据隐私、数据访问和测量的可重复性相关的问题。