Steve Gershon, MD, is Medical Director, Gershon Pain Specialists, Virginia Beach, Virginia. Acknowledgments: 3 study was received from Bruin Biometrics, LLC. Researchers received a fee for enrolling patients in the trial, and study participants received a nominal stipend upon completion of all study procedures. The authors have disclosed no other financial relationships related to this article. Submitted August 16, 2019; accepted in revised form October 22, 2019; published online ahead of print March 2, 2020.
Adv Skin Wound Care. 2020 Sep;33(9):469-475. doi: 10.1097/01.ASW.0000655380.86380.7b.
Inflammation triggered by tissue injury increases blood flow to the injured area, resulting in fluid accumulation below the epidermis known as subepidermal moisture (SEM). This accumulation can be assessed using an SEM scanner. The primary aim of this study was to determine whether levels of SEM from repeated measures at a localized area confirm the absence of a pressure injury at that site in healthy participants.
Fifty patients attending a specialized pain clinic who were at very low risk of or unaffected by pressure injuries were enrolled. Subepidermal moisture readings were gathered at the center and near-proximate to the bony prominences of the heel and sacrum.
Among the participants, repeated localized measurements did not differ significantly at or around a single anatomic site. The heel had a slightly higher variation than the sacrum, although the variance was less than 0.6 SEM units, indicating that there is likely no inflammation at these sites in patients who are not at risk of pressure injuries and who show no visual signs of localized tissue inflammation. Demographic and other potential confounder data were gathered, but no statistically significant findings emerged from these data.
The relatively flat pattern of SEM values around the bony prominences of the heels and sacrum in healthy participants supports the hypothesis that healthy tissue is not inflamed.
组织损伤引发的炎症会增加受伤区域的血流量,导致表皮下出现积液,即表皮下水分(SEM)。可以使用 SEM 扫描仪来评估这种积聚。本研究的主要目的是确定在健康参与者中,来自局部区域的 SEM 重复测量水平是否能确认该部位没有出现压力性损伤。
本研究纳入了 50 名在专门的疼痛诊所就诊的患者,他们处于发生压力性损伤的极低风险或未受压力性损伤影响。在脚跟和骶骨的中心和邻近骨突处采集 SEM 读数。
在参与者中,单一解剖部位的局部重复测量没有显著差异。脚跟处的变异略高于骶骨,尽管变异小于 0.6 SEM 单位,这表明在没有发生压力性损伤且没有局部组织炎症的视觉迹象的患者中,这些部位可能没有炎症。收集了人口统计学和其他潜在混杂因素的数据,但这些数据没有出现统计学上显著的结果。
健康参与者脚跟和骶骨骨突周围 SEM 值相对平坦的模式支持健康组织没有炎症的假设。