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运动相关性轻度创伤性脑损伤后,不到一半的患者在 2 周内康复:一项为期 2 年的前瞻性研究。

Less Than Half of Patients Recover Within 2 Weeks of Injury After a Sports-Related Mild Traumatic Brain Injury: A 2-Year Prospective Study.

机构信息

Axis Sports Medicine Specialists, Auckland, New Zealand.

Section of Epidemiology and Biostatistics, School of Population Health, University of Auckland, Auckland, New Zealand; and.

出版信息

Clin J Sport Med. 2020 Mar;30(2):96-101. doi: 10.1097/JSM.0000000000000811.

Abstract

OBJECTIVE

To describe clinical recovery time and factors that might impact on recovery after a sports-related mild traumatic brain injury (SR-mTBI; concussion).

DESIGN

Prospective cohort study (level IV evidence).

SETTING

New Zealand Sports Concussion Clinic.

PARTICIPANTS

Eight hundred twenty-two patients presenting within 14 days of a SR-mTBI/concussion over a 2-year period.

MAIN OUTCOME MEASURES

Clinical recovery measured as number of days after injury.

INTERVENTIONS METHODS

Participants were assessed and managed using a standardized protocol consisting of relative rest followed by controlled cognitive and physical loading. A reassessment was performed 14 days after injury with initiation of an active rehabilitation program consisting of a subsymptom threshold exercise program ± cervicovestibular rehabilitation (if required) for participants who remained symptomatic. Participants were then assessed every 2 weeks until clinical recovery.

RESULTS

A total of 594 participants were eligible for analysis (mean age 20.2 ± 8.7 years, 77% males) and were grouped into 3 age cohorts: children (≤12 years), adolescents (13-18 years), and adults (≥19 years). Forty-five percent of participants showed clinical recovery within 14 days of injury, 77% by 4 weeks after injury, and 96% by 8 weeks after injury. There was no significant difference in recovery time between age groups. Prolonged recovery was more common in females (P = 0.001), participants with "concussion modifiers" (P = 0.001), and with increased time between injury and the initial appointment (P = 0.003).

CONCLUSIONS

This study challenges current perceptions that most people with a SR-mTBI (concussion) recover within 10 to 14 days and that age is a determinant of recovery rate. Active rehabilitation results in high recovery rates after SR-mTBI.

摘要

目的

描述运动相关性轻度创伤性脑损伤(SR-mTBI;脑震荡)后临床康复时间及可能影响康复的因素。

设计

前瞻性队列研究(IV 级证据)。

地点

新西兰运动性脑震荡诊所。

参与者

在 2 年期间内,822 例 SR-mTBI/脑震荡后 14 天内就诊的患者。

主要观察指标

以损伤后天数衡量的临床康复情况。

干预措施

采用标准化方案对患者进行评估和管理,方案包括相对休息,然后进行受控认知和身体负荷。损伤后 14 天进行重新评估,对仍有症状的患者开始积极康复计划,包括亚症状阈运动计划+(如有需要)颈性前庭康复。随后,每 2 周评估一次,直至临床康复。

结果

共有 594 例患者符合分析条件(平均年龄 20.2 ± 8.7 岁,77%为男性),分为 3 个年龄组:儿童(≤12 岁)、青少年(13-18 岁)和成年人(≥19 岁)。45%的患者在损伤后 14 天内临床康复,77%在损伤后 4 周内康复,96%在损伤后 8 周内康复。不同年龄组之间的康复时间无显著差异。女性(P = 0.001)、有“脑震荡修正因素”(P = 0.001)和受伤至首次就诊时间延长的患者(P = 0.003)康复时间延长更常见。

结论

本研究对大多数运动相关性轻度创伤性脑损伤(脑震荡)患者在 10-14 天内康复和年龄是康复率决定因素的现有观念提出挑战。积极康复可使运动相关性轻度创伤性脑损伤后康复率较高。

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