Wesslau C, Jung K, Schirrow R
Abteilung für experimentelle Organtransplantation, Bereichs Medizin (Charité), Humboldt-Universität zu Berlin.
Z Urol Nephrol. 1988 Jun;81(6):395-400.
Two investigation methods of the renal function by means of the inulin and the endogenous creatinine clearance in narcotized and conscious rats are described in detail. The inulin clearance was 0.84 +/- 0.16 ml/min/100 g BW. The results of the creatinine clearance obtained by 6 various methods are widely different due to co-determination of foreign chromogens. Therefore, it is important to compare these results with the results of other analytical methods determining only the "true" creatinine.
详细描述了在麻醉和清醒大鼠中通过菊粉和内源性肌酐清除率来研究肾功能的两种方法。菊粉清除率为0.84±0.16毫升/分钟/100克体重。由于同时测定外来色原,通过6种不同方法获得的肌酐清除率结果差异很大。因此,将这些结果与仅测定“真实”肌酐的其他分析方法的结果进行比较很重要。