Osmers R, Goeschen K, Fuchs A R, Dennemark N
Universitätsfrauenklinik Göttingen.
Zentralbl Gynakol. 1988;110(21):1366-76.
3 ml tylose gel containing 500 micrograms PGE2 was injected into the cervical canal of 23 patients prior to first trimester abortion. 11 patients received 5 mg fenoterol orally before the PGE2-gel application and 12 patients a placebo tablet. The PGFM and oxytocin concentrations in plasma were determined radioimmunologically. The results showed the dominant role of elevated PGFM levels in the clinical prevalence of pain during induced abortion.
在孕早期流产前，向23名患者的宫颈管内注射了含500微克前列腺素E2的3毫升泰洛糖凝胶。11名患者在应用前列腺素E2凝胶前口服了5毫克非诺特罗，12名患者服用了安慰剂片。采用放射免疫法测定血浆中13,14-二氢-15-酮前列腺素F2α（PGFM）和催产素的浓度。结果表明，PGFM水平升高在人工流产时疼痛的临床发生率中起主要作用。
