Fiacchini Giacomo, Cambi Christina, Tavoni Antonio Gaetano, Bruschini Luca, Castellana Roberto, Dallan Iacopo, Berrettini Stefano
Otolaryngology, Audiology, and Phoniatric Operative Unit, Department of Surgical, Medical, Molecular Pathology, and Critical Care Medicine, Azienda Ospedaliero Universitaria Pisana, University of Pisa, Pisa, Italy.
Clinical Immunology Unit, Department of Clinical and Experimental Medicine, Azienda Ospedaliero Universitaria Pisana, University of Pisa, Pisa, Italy.
Surg J (N Y). 2020 Mar 3;6(1):e33-e36. doi: 10.1055/s-0040-1702921. eCollection 2020 Jan.
Inflammatory pseudotumor (IPT) is a rare disease that is often misinterpreted as a lymphoma or carcinoma. It may involve different body regions but most commonly the lungs and the orbital cavity. We report the case of a patient affected by an IPT of the trigeminal and facial nerves. A 69-year-old male presented to our hospital with a right facial palsy arisen suddenly 2 days before. A magnetic resonance imaging (MRI) of the head showed an abnormal mass with homogeneous enhancement involving the deep lobe of the parotid gland, the parapharyngeal space, and the infratemporal fossa, extending along the trigeminal nerve and the facial nerve. The patient was planned for multiple transnasal biopsies in the nasopharynx, the region of the foramen ovale, and the deep lobe of the parotid gland, but the results were inconclusive, with no evidence of a malignant process. We considered the possibility that the lesion could be an IPT, and the patient was treated with prednisone and cyclophosphamide. Three months after the conclusion of the treatment, an MRI showed a complete radiological response.
炎性假瘤（IPT）是一种罕见疾病，常被误诊为淋巴瘤或癌。它可累及身体不同部位，但最常见于肺部和眼眶。我们报告一例三叉神经和面神经炎性假瘤患者。一名69岁男性因2天前突然出现右侧面瘫就诊于我院。头部磁共振成像（MRI）显示一个异常肿块，呈均匀强化，累及腮腺深叶、咽旁间隙和颞下窝，沿三叉神经和面神经延伸。计划对患者进行鼻咽部、卵圆孔区域和腮腺深叶的多次经鼻活检，但结果不明确，未发现恶性病变证据。我们考虑该病变可能为炎性假瘤，遂给予患者泼尼松和环磷酰胺治疗。治疗结束3个月后，MRI显示影像学完全缓解。
