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播散性腹膜平滑肌瘤病:一种罕见的腹腔内病变表现,酷似播散性恶性肿瘤。

Disseminated peritoneal leiomyomatosis: an unusual presentation of intra-abdominal lesion mimicking disseminated malignancy.

作者信息

Soni Sweta, Pareek Puneet, Narayan Satya

机构信息

Department of Radiation Oncology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

出版信息

Med Pharm Rep. 2020 Jan;93(1):113-116. doi: 10.15386/mpr-1421. Epub 2020 Jan 31.

Abstract

Leiomyoma are commonly seen as benign smooth muscle tumors of the uterus. Smooth muscle tumors with unusual growth pattern are rare and include 3 primary neoplasms: intravenous leiomyomatosis (IVL), benign metastasizing leiomyoma (BML) and disseminated peritoneal leiomyomatosis (DPL). DPL is a rare benign disease, often giving the appearance of metastatic ovarian or peritoneal carcinoma. It is a disease that predominately affects women at their reproductive age. The risk of malignant transformation is 2-5%. There are no standard treatment guidelines for the management of the DPL. The unusual presentation of the disease delays the diagnosis or is often misdiagnosed and thus over treated, which may lead to increased morbidity and mortality. Therefore careful consideration and high index of suspicion is required for the proper management of such cases.

摘要

平滑肌瘤通常被视为子宫的良性平滑肌肿瘤。具有异常生长模式的平滑肌肿瘤较为罕见,包括3种原发性肿瘤:静脉内平滑肌瘤病(IVL)、良性转移性平滑肌瘤(BML)和播散性腹膜平滑肌瘤病(DPL)。DPL是一种罕见的良性疾病,常表现为转移性卵巢癌或腹膜癌。该疾病主要影响育龄期女性。恶性转化风险为2%-5%。对于DPL的管理,目前尚无标准治疗指南。该疾病的不典型表现会延迟诊断或常被误诊,进而过度治疗,这可能导致发病率和死亡率增加。因此,对于此类病例的正确管理需要仔细考虑并保持高度怀疑指数。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db9c/7051819/63f3a90c1738/cm-93-113f1.jpg

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