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双侧序贯肺移植后快速进展性肺卡波西肉瘤:1 例报告。

Rapidly Progressive Pulmonary Kaposi Sarcoma After Bilateral Sequential Lung Transplant: A Case Report.

机构信息

From the Department of Thoracic Surgery and Lung Transplantation, Ankara City Hospital, University of Health Sciences, Ankara, Turkey.

出版信息

Exp Clin Transplant. 2022 May;20(5):537-540. doi: 10.6002/ect.2019.0246. Epub 2020 Mar 4.

Abstract

Skin cancers are among the rarely seen complications after solid-organ transplant. Kaposi sarcoma invasion to an allograft is an uncommon condition. In this study, we present a case of Kaposi sarcoma in a 58-year-old patient diagnosed at 8 months after bilateral sequential lung transplant due to chronic obstructive pulmonary disease. Kaposi sarcoma showed rapid progression despite immunosuppressive drug modification, resulting in lung involvement and respiratory failure. Rapid and complete improvement was achieved with rapid diagnosis and aggressive treatment that included combined chemotherapy after surgery. The patient presented with no complications from Kaposi sarcoma at month 26 after transplant.

摘要

皮肤癌是实体器官移植后罕见的并发症之一。卡波西肉瘤侵犯移植物是一种罕见的情况。在本研究中,我们报告了一例慢性阻塞性肺疾病患者在接受双侧序贯肺移植 8 个月后诊断为卡波西肉瘤的病例。尽管免疫抑制药物进行了调整,卡波西肉瘤仍迅速进展,导致肺部受累和呼吸衰竭。通过快速诊断和积极治疗(包括手术后联合化疗),卡波西肉瘤迅速完全缓解。移植后 26 个月,患者无卡波西肉瘤并发症。

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