糖尿病在胆囊和胆道疾病中的作用。
The Role of Diabetes Mellitus in Diseases of the Gallbladder and Biliary Tract.
作者信息
Rahmani Benjamin, Gandhi Jason, Joshi Gunjan, Smith Noel L, Reid Inefta, Khan Sardar Ali
机构信息
Department of Physiology and Biophysics, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, USA
Medical Student Research Institute, St. George’s University School of Medicine, Grenada, West Indies
出版信息
Curr Diabetes Rev. 2020;16(9):931-948. doi: 10.2174/1573399816666200305094727.
BACKGROUND
The increasing prevalence of diabetes mellitus worldwide continues to pose a heavy burden. Though its gastrointestinal impact is appropriately recognized, the lesser known associations may be overlooked.
OBJECTIVE
We aim to review the negative implications of diabetes on the gallbladder and the biliary tract.
METHODS
A MEDLINE® database search of literature was conducted with emphasis on the previous five years, combining keywords such as "diabetes," "gallbladder," and "biliary".
RESULTS
The association of diabetes to the formation of gallstones, gallbladder cancer, and cancer of the biliary tract are discussed along with diagnosis and treatment.
CONCLUSION
Though we uncover the role of diabetic neuropathy in gallbladder and biliary complications, the specific individual diabetic risk factors behind these developments is unclear. Also, in addition to diabetes control and surgical gallbladder management, the treatment approach also requires further focus.
背景
全球糖尿病患病率不断上升，持续造成沉重负担。尽管其对胃肠道的影响已得到充分认识，但鲜为人知的关联可能被忽视。
目的
我们旨在综述糖尿病对胆囊和胆道的负面影响。
方法
对MEDLINE®数据库进行文献检索，重点关注过去五年，结合“糖尿病”“胆囊”和“胆道”等关键词。
结果
讨论了糖尿病与胆结石形成、胆囊癌和胆管癌的关联以及诊断和治疗。
结论
尽管我们揭示了糖尿病神经病变在胆囊和胆道并发症中的作用，但这些病变背后具体的个体糖尿病风险因素尚不清楚。此外，除了糖尿病控制和胆囊手术管理外，治疗方法还需要进一步关注。
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