Department of Radiology, Kochi Medical School, Kochi University, Nankoku, Japan.
Department of Urology, Kochi Medical School, Kochi University, Nankoku, Japan.
Minim Invasive Ther Allied Technol. 2021 Dec;30(6):327-333. doi: 10.1080/13645706.2020.1734622. Epub 2020 Mar 5.
To evaluate the effectiveness of the transarterial infusion of iodized oil and gelatin particles for marking before CT-guided percutaneous cryoablation (PCA) in patients with renal cell carcinoma (RCC).
This study included ten patients (seven men, three women; mean age 53 years) with 13 RCCs between July 2016 and September 2017. The transarterial infusion of iodized oil and gelatin particles was considered successful when iodized oil accumulated in the target area on CT. CT value of the tumor before and after marking was measured and two diagnostic radiologists evaluated the visualization scores by using a five-point scale (5 = excellent to 1 = invisible).
Preoperative marking was successful in all 13 tumors; the median visualization score was 5 post-lipiodol marking and 4 at the time of PCA. The mean CT density was 597 ± 371 Hounsfield units (HU) just after marking and 437 ± 234 HU at the time of PCA. All 13 CT-guided PCA procedures were successful. There were no significant complications. During follow-up (median 11.5 ± 7.0 months) there were no local recurrences.
As the transarterial infusion of iodized oil and gelatin particles improved RCC visualization on CT, its delivery before CT-guided PCA may improve its safety and success rate in patients with RCC.
评估经动脉碘化油和明胶微球灌注在 CT 引导下经皮冷冻消融（PCA）前对标记肾细胞癌（RCC）的效果。
本研究纳入了 2016 年 7 月至 2017 年 9 月期间的 10 名患者（7 名男性，3 名女性；平均年龄 53 岁），共 13 个 RCC。当碘油在 CT 上积聚在目标区域时，认为经动脉碘化油和明胶微球灌注是成功的。测量肿瘤在标记前后的 CT 值，并由两名诊断放射科医生使用五分制（5=极好至 1=不可见）评估可视化评分。
13 个肿瘤的术前标记均成功；碘油标记后中位数的可视化评分为 5 分，PCA 时为 4 分。标记后平均 CT 密度为 597±371 亨氏单位（HU），PCA 时为 437±234 HU。所有 13 例 CT 引导下 PCA 手术均成功。无明显并发症。在随访期间（中位数 11.5±7.0 个月），无局部复发。
经动脉碘化油和明胶微球灌注可改善 CT 上 RCC 的可视化效果，在 CT 引导下 PCA 前使用可能会提高 RCC 患者的安全性和成功率。
