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体外膜肺氧合用于支持急性暴发性心肌炎的儿科患者。

Extracorporeal membrane oxygenation for the support of pediatric patients with acute fulminant myocarditis.

作者信息

Şık Güntülü, Annayev Agageldi, Demirbuğa Asuman, Deliceo Elif, Aydın Selim, Erek Ersin, Demir Halil İbrahim, Çıtak Agop

机构信息

Departments of Pediatric Intensive Care Unit, Acıbadem Mehmet Ali Aydınlar University, School of Medicine, İstanbul, Turkey.

Departments of Cardiovascular Surgery, Acıbadem Mehmet Ali Aydınlar University, School of Medicine, İstanbul, Turkey.

出版信息

Turk J Pediatr. 2019;61(6):867-872. doi: 10.24953/turkjped.2019.06.007.

DOI:10.24953/turkjped.2019.06.007
PMID:32134580
Abstract

Şık G, Annayev A, Demirbuğa A, Deliceo E, Aydın S, Erek E, Demir Hİ, Çıtak A. Extracorporeal membrane oxygenation for the support of pediatric patients with acute fulminant myocarditis. Turk J Pediatr 2019; 61: 867-872. Acute fulminant myocarditis, is a severe, rapidly progressive disease. The clinical outcomes of children with severe acute myocarditis who are resist to medical treatment is not well known. We studied the clinical courses of patients with acute fulminant myocarditis supported by extracorporeal membrane oxygenation (ECMO). We performed a retrospective chart review of six children with acute fulminant myocarditis who were treated with ECMO. Demographic information, clinical and vital signs, as well as laboratory results were investigated. The median age of 63 months (13-140 months), the mean ECMO duration was 164 hours (79-402 hours), and median intensive care unit stay was 24 days. The most common symptoms were chest pain (66%) and fever (66%). Severe arrhythmia were seen in two patients. One patient received extracorporeal cardiopulmonary resuscitation. In two patients, right femoral arteries and right femoral veins were used, in others, right common carotid artery and right internal jugular veins were used. Five patients (83.3 %) survived to discharge. ECMO can be used effectively in pediatric patients with acute fulminant myocarditis to support the circulation while awaiting myocardial recovery. Timely use of ECMO can improve the survival rate and may be associated with better outcomes.

摘要

希克G、安娜耶夫A、德米尔布加A、德利乔E、艾登S、埃雷克E、德米尔Hİ、奇塔克A。体外膜肺氧合支持小儿急性暴发性心肌炎患者。《土耳其儿科学杂志》2019年;61:867 - 872。急性暴发性心肌炎是一种严重、进展迅速的疾病。对药物治疗耐药的重症急性心肌炎患儿的临床结局尚不清楚。我们研究了接受体外膜肺氧合(ECMO)支持的急性暴发性心肌炎患者的临床病程。我们对6例接受ECMO治疗的急性暴发性心肌炎患儿进行了回顾性病历审查。调查了人口统计学信息、临床和生命体征以及实验室结果。中位年龄为63个月(13 - 140个月),平均ECMO持续时间为164小时(79 - 402小时),中位重症监护病房住院时间为24天。最常见的症状是胸痛(66%)和发热(66%)。2例患者出现严重心律失常。1例患者接受了体外心肺复苏。2例患者使用右股动脉和右股静脉,其他患者使用右颈总动脉和右颈内静脉。5例患者(83.3%)存活出院。ECMO可有效用于小儿急性暴发性心肌炎患者,在等待心肌恢复期间支持循环。及时使用ECMO可提高生存率,并可能带来更好的结局。

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